Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL154990 | 0.87 | CA4 (0.41) | CA1MEN1ALDH1A1TSHRKMT2A | |
| Acetic Acid SCHEMBL8458828 | 0.85 | CA1 (0.56) | CA1MEN1ALDH1A1TSHRKMT2A | |
| Methacrylic Acid SCHEMBL27130007 | 0.83 | CA4 (0.38) | CA1ALDH1A1TSHRFFAR3HDAC3 | |
| Acetic Acid SCHEMBL8723844 | 0.82 | CA1 (0.53) | CA1MEN1ALDH1A1TSHRKMT2A | |
| Methacrylic Acid SCHEMBL27040264 | 0.81 | CA4 (0.36) | CA1ALDH1A1FFAR3HDAC3HDAC1 | |
| Bromide SCHEMBL31153362 | 0.77 | — | — | |
| Hydrogen Sulfide SCHEMBL28557576 | 0.77 | — | — | |
| SCHEMBL29468599 | 0.77 | — | — | |
| Water SCHEMBL2168446 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL29878467 | 0.77 | TSHR (0.40) | CA1MEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106336485-A | Anti-mud type low-slump-loss polycarboxylic acid water reducing agent and preparation method thereof | 河北三楷深发科技股份有限公司 | 2017-01-18 | — | — | CN | disclosed |