⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22651966 | 1.00 | — | — | |
| SCHEMBL18103346 | 0.84 | DNM1 (0.35) | — | |
| SCHEMBL24768942 | 0.82 | PRSS1 (0.39) | — | |
| SCHEMBL5932723 | 0.80 | — | — | |
| SCHEMBL10801106 | 0.79 | — | — | |
| SCHEMBL27848072 | 0.79 | — | — | |
| SCHEMBL16079398 | 0.77 | — | — | |
| SCHEMBL15499154 | 0.77 | — | — | |
| SCHEMBL13669535 | 0.77 | — | — | |
| SCHEMBL18638282 | 0.76 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239058-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2021-12-02 | — | — | WO | disclosed |
| EP-3219312-B1 | ION BINDING POLYMERS AND USES THEREOF | RELYPSA INC (US) | 2019-01-30 | — | — | EP | disclosed |
| US-9642352-B2 | Method of preparing embryos or blastocysts for cryopreservation | MARIPOSA BIOTECHNOLOGY, INC. (US) | 2017-05-09 | — | — | US | disclosed |
| US-9617224-B2 | Five-membered heterocycles useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-04-11 | — | — | US | disclosed |
| US-20170013826-A1 | METHOD OF PREPARING EMBRYOS FOR CRYOPRESERVATION | MARIPOSA BIOTECHNOLOGY, INC. (US) | 2017-01-19 | — | — | US | disclosed |
| US-20170013827-A1 | METHOD OF PREPARING BLASTOCYSTS FOR CRYOPRESERVATION | MARIPOSA BIOTECHNOLOGY, INC. (US) | 2017-01-19 | — | — | US | disclosed |
| US-9512148-B2 | Boron-containing diacylhydrazines | INTREXON CORPORATION (US) | 2016-12-06 | — | — | US | disclosed |
| US-9303058-B2 | Betulonic and betulinic acid derivatives | Leunis, Jean-Claude (BE) | 2016-04-05 | — | — | US | disclosed |
| US-20150322092-A1 | Boron-Containing Diacylhydrazines | INTREXON CORPORATION (US) | 2015-11-12 | — | — | US | disclosed |
| US-20140066416-A1 | BETULONIC AND BETULINIC ACID DERIVATIVES | Leunis, Jean-Claude (BE) | 2014-03-06 | — | — | US | disclosed |