⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1470942 | 0.82 | — | — | |
| SCHEMBL2058560 | 0.82 | TDP1 (0.41) | — | |
| SCHEMBL4772280 | 0.78 | TDP1 (0.40) | — | |
| SCHEMBL14700345 | 0.78 | TDP1 (0.40) | — | |
| SCHEMBL1473098 | 0.76 | — | — | |
| SCHEMBL101773 | 0.76 | — | — | |
| SCHEMBL331879 | 0.75 | — | — | |
| SCHEMBL2058044 | 0.73 | TDP1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL18130992 | 0.73 | — | — | |
| SCHEMBL19818261 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912150-B2 | Ribosome structure and protein synthesis inhibitors | MELINTA THERAPEUTICS, INC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-20140066623-A1 | Ribosome Structure and Protein Synthesis Inhibitors | MELINTA THERAPEUTICS, LLC | 2014-03-06 | — | — | US | disclosed |