SCHEMBL4772280

SCHEMBL4772280

CSCCCSCCCO

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 1/20 0.32
TRPA1 O75762 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14700345 0.89 TDP1 (0.40) TDP1ALDH1A1SMN1; SMN2
SCHEMBL101773 0.88
Hydrochloric Acid SCHEMBL18130992 0.85
SCHEMBL3070831 0.85 TRPA1 (0.38) TDP1TRPA1
SCHEMBL3071359 0.85 TRPA1 (0.38) TDP1TRPA1
SCHEMBL21676203 0.83 TDP1 (0.56) TDP1TRPA1
SCHEMBL3069312 0.82 TRPA1 (0.36) TDP1TRPA1
Phosphoric Acid SCHEMBL11081081 0.82 BHMT (0.32) TDP1TRPA1
SCHEMBL331879 0.82
SCHEMBL283183 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1908788-A1 Novel biomimetic hydrogel materials The Regents of the University of California (US) 2008-04-09 EP disclosed
EP-1017737-B1 NOVEL BIOMIMETIC HYDROGEL MATERIALS UNIV CALIFORNIA (US) 2008-01-23 EP disclosed
US-6552103-B1 Soft contact lenses and biomedical implants THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-04-22 US disclosed
EP-1017737-A4 NOVEL BIOMIMETIC HYDROGEL MATERIALS UNIV CALIFORNIA (US) 2002-06-26 EP disclosed
US-6107365-A A COPOLYMER OF METHACRYLATE FUNCTIONAL SULFOXIDE, SULFIDE OR SULFONE MONOMERS AND A COMONOMER SELECTED FROM HYDROPHILIC OR HYDROPHOBIC MATERIAL SELECTED FROM ACRYLMIDE, ACRYLATE, METHACRYLATE, SILOXANE, VINYL AND A DERIVATIVE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-08-22 US disclosed
EP-1017737-A1 NOVEL BIOMIMETIC HYDROGEL MATERIALS The Regents of the University of California (US) 2000-07-12 EP disclosed
WO-1999011692-A1 NOVEL BIOMIMETIC HYDROGEL MATERIALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1999-03-11 WO disclosed