SCHEMBL17685197

CC(C)(C)OC(=O)CC[C@H](NC(=O)N[C@@H](CCC(=O)N[C@@H](CCCCN(Cc1nccn1CC(=O)N(CC(=O)OC(C)(C)C)CC(=O)OC(C)(C)C)Cc1nccn1CC(=O)N(CC(=O)OC(C)(C)C)CC(=O)OC(C)(C)C)CC(=O)O)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	FOLH1	Q04609	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15501039	0.93	FPR2 (0.32)	FOLH1
SCHEMBL17685198	0.93	—	—
SCHEMBL2831636	0.92	FOLH1 (0.35)	FOLH1
SCHEMBL17690558	0.92	FOLH1 (0.35)	FOLH1
SCHEMBL13237046	0.91	FOLH1 (0.36)	FOLH1
SCHEMBL11936778	0.89	—	—
SCHEMBL13287694	0.89	CTSK (0.31)	—
SCHEMBL2832354	0.86	SIRT2 (0.37)	FOLH1
SCHEMBL2835915	0.84	FOLH1 (0.36)	FOLH1
SCHEMBL1742288	0.84	TDP1 (0.34)	FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2706057-B1	Bis(imidazolyl)compounds and radionuclide complexes	MOLECULAR INSIGHT PHARM INC (US)	2016-04-20	—	—	EP	claimed