Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 12/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469091 | 0.95 | F2R (0.69) | F2RMEN1KMT2AGAATP53 | |
| SCHEMBL14468892 | 0.92 | F2R (0.82) | F2RMEN1KMT2AGAATP53 | |
| SCHEMBL14449192 | 0.90 | F2R (0.85) | F2RMEN1KMT2AGAATP53 | |
| Hydrochloric Acid SCHEMBL1728795 | 0.90 | F2R (0.84) | F2RMEN1KMT2AGAATP53 | |
| SCHEMBL14468996 | 0.87 | F2R (0.55) | F2RGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL14468874 | 0.87 | F2R (0.81) | F2RMEN1KMT2AGAATP53 | |
| SCHEMBL12167175 | 0.87 | F2R (0.81) | F2RMEN1KMT2AGAATP53 | |
| SCHEMBL14469006 | 0.85 | F2R (0.71) | F2RGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL12151780 | 0.84 | F2R (0.58) | F2R | |
| SCHEMBL14468873 | 0.84 | F2R (0.57) | F2RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385039-B1 | 2-Iminoisoindolinone derivatives as thrombin receptor antagonists | EISAI R&D MAN CO LTD (JP) | 2014-03-12 | — | — | EP | disclosed |