SCHEMBL15503545

SCHEMBL15503545

O=C(CCC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NCCOCCO)NCCOCCO

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TLR2 O60603 6/20 0.52
▸ KMT2A Q03164 2/20 0.44
▸ MDM4 O15151 1/20 0.42
▸ TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29799568 0.91 KMT2A (0.51) TLR2KMT2AMDM4TP53
SCHEMBL26232004 0.91 KMT2A (0.51) TLR2KMT2AMDM4TP53
SCHEMBL29083314 0.87 TLR2 (0.45) TLR2
SCHEMBL25835723 0.87 TLR2 (0.61) TLR2
SCHEMBL26232005 0.87 TLR2 (0.45) TLR2
SCHEMBL29716713 0.87 TLR2 (0.45) TLR2
SCHEMBL25848801 0.86 TLR2 (0.57) TLR2KMT2A
SCHEMBL25835749 0.86 TLR2 (0.60) TLR2
SCHEMBL26689396 0.85 KMT2A (0.53) TLR2KMT2AMDM4TP53
SCHEMBL26689241 0.85 KMT2A (0.53) TLR2KMT2AMDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140072513-A1 SUGAR AND PEG FUNCTIONALIZED POLYACETALS WITH CONTROLLED PH-DEPENDENT DEGRADATION ARGON PHARMA S.L. (ES) 2014-03-13 — — US disclosed
US-20140072513-A1 SUGAR AND PEG FUNCTIONALIZED POLYACETALS WITH CONTROLLED PH-DEPENDENT DEGRADATION ARGON PHARMA S.L. (ES) 2014-03-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140072513-A1 SUGAR AND PEG FUNCTIONALIZED POLYACETALS WITH CONTROLLED PH-DEPENDENT DEGRADATION CD44, PGD, H1-3 TLR2 1420/4885KMT2A 2589/4885MDM4 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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