Glycyl Proline

Glycyl Proline

SCHEMBL155067

NCC(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.62

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE P12821 10/20 0.62
DPP4 P27487 1/20 0.56
PREP P48147 1/20 0.56
FAP Q12884 1/20 0.56
DPP8 Q6V1X1 1/20 0.56
DPP9 Q86TI2 1/20 0.56
MVD P53602 2/20 0.51
REN P00797 3/20 0.50
LMNA P02545 2/20 0.50
HSD17B10 Q99714 2/20 0.50
CYP2C19 P33261 1/20 0.50
KDM4E B2RXH2 1/20 0.50
F2 P00734 1/20 0.50
LTA4H P09960 1/20 0.50
MAPT P10636 1/20 0.50
PEPD P12955 1/20 0.50
ALOX15 P16050 1/20 0.50
PTGS1 P23219 1/20 0.50
HTR2A P28223 1/20 0.50
PTGS2 P35354 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycyl Proline SCHEMBL30051559 1.00 ACE (0.62) ACEDPP4PREPFAPDPP8
Glycyl Proline SCHEMBL155066 1.00 ACE (0.62) ACEDPP4PREPFAPDPP8
Glycyl Proline SCHEMBL4168006 0.98 ACE (0.60) ACEDPP4PREPFAPDPP8
Glycyl Proline SCHEMBL4167998 0.98 ACE (0.60) ACEDPP4PREPFAPDPP8
Glycyl Proline SCHEMBL28116179 0.96 ACE (0.58) ACEDPP4PREPFAPDPP8
Glycyl Proline SCHEMBL28116177 0.96 ACE (0.58) ACEDPP4PREPFAPDPP8
SCHEMBL31364129 0.94 ACE (0.56) ACEDPP4PREPFAPDPP8
SCHEMBL10656884 0.93 ACE (0.55) ACEDPP4PREPFAPDPP8
SCHEMBL29777459 0.93 ACE (0.55) ACEDPP4PREPFAPDPP8
Glycyl Proline SCHEMBL6660425 0.90 ACE (0.53) ACEDPP4PREPFAPDPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1774 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743102-A1 COLLAGEN PEPTIDE COMPOSITION AND USE THEREOF IN AMELIORATING NEUROLOGICAL CONDITIONS AND FIBROSIS Rousselot BV (BE) 2026-05-20 EP claimed
EP-4003288-B1 COSMETIC COMPOSITION WITH COMBINED FILLER AND SKIN REGENERATIVE EFFECT GIULIANI SPA (IT) 2026-05-06 EP claimed
WO-2026090513-A1 FIBROBLAST ACTIVATION PROTEIN TARGETING NANOPARTICLES AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2026-04-30 WO claimed
EP-4733308-A1 FAP-TARGETING COMPOUND, AND RADIONUCLIDE-LABELED COMPLEX BASED THEREON, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2026-04-29 EP claimed
US-20260103700-A1 REGULATION OF RAN TRANSLATION BY PKR AND EIF2A-P PATHWAYS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2026-04-16 US claimed
EP-4719486-A1 CONJUGATES AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
EP-4719498-A1 RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
US-12576154-B2 Conjugates of PSMA-binding moieties with cytotoxic agents PHILOCHEM AG (CH) 2026-03-17 US claimed
CN-121577901-A Urine metabolism marker combination for distinguishing benign kidney diseases from kidney cancers and application thereof 哈尔滨脉图精准技术有限公司 2026-02-27 CN claimed
EP-4687866-A1 INHIBITORS OF ETS2-ACTIVATING MOLECULES FOR THE TREATMENT OF INFLAMMATORY DISEASES The Francis Crick Institute Limited (GB) 2026-02-11 EP claimed
EP-0618235-A1 Process for the synthesis of semisynthetic glycosaminoglycans containig alpha-L-galacturonic acid substituted with nucleophilic radicals in position 3 ALFA WASSERMANN S.p.A. (IT) 1994-10-05 EP claimed
EP-0618234-A1 Process for the synthesis of semisynthetic glycosaminoglycans with heparin or heparan structure modified in position 2 of the alpha-L-iduronic-2-0-sulfate acid ALFA WASSERMANN S.p.A. (IT) 1994-10-05 EP claimed
EP-0416282-B1 Microbiologically produced N-Acyl-L-proline-acylase, process for its production and its use DEGUSSA (DE) 1994-09-14 EP claimed
EP-0565863-A2 Semi-synthetic glycosaminoglycans with heparin or heparan structure of alpha-L-iduronic-2-0-sulfate acid modified in position 2 ALFA WASSERMANN S.p.A. (IT) 1993-10-20 EP claimed
EP-0565862-A2 Semi-synthetic glycosaminoglycans containing alpha-L-galacturonic acid substituted with nucleophilic radicals in position 3 ALFA WASSERMANN S.p.A. (IT) 1993-10-20 EP claimed
US-5219741-A Reacting in the presence of microbiologically produced N-acyl-L-proline acylase DEGUSSA AG (DE) 1993-06-15 US claimed
US-5120652-A Synthesis of proline from acyl derivatives; thermostable DEGUSSA AG (DE) 1992-06-09 US claimed
US-4427762-A DEVELOPMENT WITH ALKALINE DEVELOPER MIXTURE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-01-24 US claimed
EP-0082015-A1 Method of forming an image with a photographic cuprous halide material KONICA CORPORATION (JP) 1983-06-22 EP claimed
US-4085207-A AND AT LEAST ONE OF N-ACYL-L-TRYPTOPHANS AND N-ACYL-L-PROLINES OTSUKA PHARMACEUTICAL FACTORY, INC. (JA) 1978-04-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576154-B2 Conjugates of PSMA-binding moieties with cytotoxic agents PCNA, ENPEP, PSMA3 ACE 3096/4885DPP4 648/4885PREP 278/4885
US-20260103700-A1 REGULATION OF RAN TRANSLATION BY PKR AND EIF2A-P PATHWAYS EIF2A, EIF2AK1, EIF2AK3 ACE 4590/4885DPP4 3318/4885PREP 2071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.