Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | MVD | P53602 | 2/20 | 0.45 |
| ▸ | REN | P00797 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PEPD | P12955 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycyl Proline SCHEMBL30051559 | 0.90 | ACE (0.62) | ACEDPP4PREPFAPDPP8 | |
| Glycyl Proline SCHEMBL155067 | 0.90 | ACE (0.62) | ACEDPP4PREPFAPDPP8 | |
| Glycyl Proline SCHEMBL155066 | 0.90 | ACE (0.62) | ACEDPP4PREPFAPDPP8 | |
| Glycyl Proline SCHEMBL4167998 | 0.89 | ACE (0.60) | ACEDPP4PREPFAPDPP8 | |
| Glycyl Proline SCHEMBL4168006 | 0.89 | ACE (0.60) | ACEDPP4PREPFAPDPP8 | |
| Glycyl Proline SCHEMBL28116179 | 0.87 | ACE (0.58) | ACEDPP4PREPFAPDPP8 | |
| Glycyl Proline SCHEMBL28116177 | 0.87 | ACE (0.58) | ACEDPP4PREPFAPDPP8 | |
| SCHEMBL31364129 | 0.85 | ACE (0.56) | ACEDPP4PREPFAPDPP8 | |
| SCHEMBL10656884 | 0.84 | ACE (0.55) | ACEDPP4PREPFAPDPP8 | |
| SCHEMBL29777459 | 0.84 | ACE (0.55) | ACEDPP4PREPFAPDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087935-B1 | ANTHRACENE DERIVATIVES AS ANTI-CANCER AGENTS | BTG INT LTD (GB) | 2004-08-18 | — | — | EP | disclosed |
| US-20030203975-A1 | Anti-cancer agents | BTG INTERNATIONAL LIMITED (GB) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203975-A1 | Anti-cancer agents | TOP2B, TOP2A, TOP1 | ACE 1827/4885DPP4 3236/4885PREP 1647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.