Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 18/20 | 0.39 |
| ▸ | BCHE | P06276 | 12/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15509929 | 0.89 | ACHE (0.41) | ACHEBCHEEPHX2 | |
| SCHEMBL2532410 | 0.86 | NR4A1 (0.33) | ACHEBCHEEPHX2 | |
| SCHEMBL15509717 | 0.85 | HTT (0.43) | ACHEBCHE | |
| SCHEMBL15510703 | 0.85 | GAA (0.41) | ACHEBCHE | |
| SCHEMBL15509518 | 0.85 | ACHE (0.40) | ACHEBCHE | |
| SCHEMBL15509947 | 0.85 | TSHR (0.45) | ACHEBCHE | |
| SCHEMBL15509585 | 0.84 | TSHR (0.47) | ACHEBCHE | |
| SCHEMBL15509535 | 0.84 | KDM4E (0.45) | ACHEBCHE | |
| SCHEMBL15510031 | 0.84 | MEN1 (0.42) | ACHEBCHEEPHX2 | |
| SCHEMBL27905174 | 0.84 | EPHX2 (0.41) | ACHEBCHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558449-B1 | NOVEL 3,3-DIMETHYL TETRAHYDROQUINOLINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2014-03-05 | — | — | EP | claimed |