SCHEMBL15510403

SCHEMBL15510403

S=C(Nc1cccnc1)Nc1cccnc1

nearest known ligand 0.89

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.74
KDM4E B2RXH2 9/20 0.72
KMT2A Q03164 2/20 0.70
PKM P14618 1/20 0.70
ALDH1A1 P00352 7/20 0.68
HPGD P15428 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.66
MEN1 O00255 1/20 0.64
LMNA P02545 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11186307 0.94 PKM (0.69) MAPTKDM4EKMT2APKMALDH1A1
SCHEMBL23220314 0.88 MAPT (0.61) MAPTKDM4EKMT2APKMALDH1A1
SCHEMBL14031230 0.88 MAPT (0.61) MAPTKDM4EKMT2APKMALDH1A1
SCHEMBL6815668 0.88 MAPT (0.66) MAPTKDM4EKMT2APKMALDH1A1
SCHEMBL30394839 0.85 MAPT (0.58) MAPTKDM4EKMT2APKMALDH1A1
SCHEMBL18292322 0.85 TSHR (0.68) MAPTKDM4EKMT2APKMALDH1A1
SCHEMBL16566452 0.85 MAPT (0.70) MAPTKDM4EKMT2APKMALDH1A1
SCHEMBL17727775 0.84 MAPT (0.56) MAPTKDM4EKMT2APKMALDH1A1
SCHEMBL4681932 0.84 MAPT (0.56) MAPTKDM4EKMT2APKMALDH1A1
SCHEMBL11156215 0.84 ALDH1A1 (0.57) MAPTKDM4EKMT2APKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2703062-B1 METHOD FOR ABSORBING ACID COMPOUNDS CONTAINED IN A GASEOUS EFFLUENT BY MEANS OF AN AMINE-BASED AQUEOUS SOLUTION IFP ENERGIES NOW (FR) 2022-10-12 EP disclosed
US-10137404-B2 Method of absorbing acid compounds contained in a gaseous effluent using an amine-based aqueous solution IFP Energies Nouvelles (FR) 2018-11-27 US disclosed
WO-2016196514-A1 THIOUREA CATALYSTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2016-12-08 WO disclosed
US-20140060328-A1 METHOD OF ABSORBING ACID COMPOUNDS CONTAINED IN A GASEOUS EFFLUENT USING AN AMINE-BASED AQUEOUS SOLUTION IFP Energies Nouvelles (FR) 2014-03-06 US disclosed
EP-2703062-A2 Method for absorbing acid compounds contained in a gaseous effluent by means of an amine-based aqueous solution IFP Energies nouvelles (FR) 2014-03-05 EP disclosed