Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15498178 | 1.00 | NR1I2 (0.63) | NR1I2CYP2E1 | |
| SCHEMBL12909749 | 0.97 | NR1I2 (0.63) | NR1I2CYP2E1 | |
| SCHEMBL12909750 | 0.97 | NR1I2 (0.63) | NR1I2CYP2E1 | |
| SCHEMBL12909596 | 0.96 | NR1I2 (0.62) | NR1I2CYP2E1 | |
| SCHEMBL12910227 | 0.95 | NR1I2 (0.58) | NR1I2CYP2E1 | |
| SCHEMBL12909609 | 0.95 | CYP2E1 (0.59) | NR1I2CYP2E1 | |
| SCHEMBL12909921 | 0.95 | NR1I2 (0.58) | NR1I2CYP2E1 | |
| SCHEMBL937641 | 0.95 | NR1I2 (0.58) | NR1I2CYP2E1 | |
| SCHEMBL937315 | 0.95 | CYP2E1 (0.59) | NR1I2CYP2E1 | |
| SCHEMBL937317 | 0.95 | CYP2E1 (0.59) | NR1I2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140065103-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRIDAE VIRAL INFECTIONS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140065103-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRIDAE VIRAL INFECTIONS | GOT1, RNASE1, SLC10A1 | NR1I2 1347/4885CYP2E1 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.