Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HK1 | P19367 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15512392 | 0.96 | PTGDR2 (0.40) | PTGDR2ALDH1A1HK1SMN1; SMN2HKDC1 | |
| SCHEMBL15513159 | 0.95 | MEN1 (0.40) | PTGDR2ALDH1A1HK1SMN1; SMN2HKDC1 | |
| SCHEMBL15512809 | 0.92 | PTGDR2 (0.40) | PTGDR2ALDH1A1HK1HKDC1PTGDR | |
| SCHEMBL15512357 | 0.88 | PTGDR2 (0.39) | PTGDR2ALDH1A1HK1HKDC1PTGDR | |
| SCHEMBL3277161 | 0.88 | TP53 (0.47) | PTGDR2ALDH1A1HK1SMN1; SMN2HKDC1 | |
| SCHEMBL15512880 | 0.87 | POLB (0.41) | PTGDR2TP53MEN1KMT2A | |
| SCHEMBL3277265 | 0.86 | MEN1 (0.46) | PTGDR2ALDH1A1HK1SMN1; SMN2HKDC1 | |
| SCHEMBL15512702 | 0.85 | PTGDR2 (0.40) | PTGDR2PTGDRPTGIRTP53 | |
| SCHEMBL3276383 | 0.84 | POLB (0.49) | ALDH1A1HK1SMN1; SMN2HKDC1TP53 | |
| SCHEMBL15512537 | 0.83 | PER2 (0.44) | PTGDR2PTGDRPTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966134-B1 | NOVEL FUSED PYRROLE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2014-03-12 | — | — | EP | claimed |