Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | PPARG | P37231 | 3/20 | 0.61 |
| ▸ | PPARD | Q03181 | 3/20 | 0.61 |
| ▸ | PPARA | Q07869 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | FABP4 | P15090 | 2/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17333296 | 0.88 | HSP90AA1 (0.64) | PTPN1PPARGPPARDPPARAKMT2A | |
| SCHEMBL17333429 | 0.86 | — | — | |
| SCHEMBL10488884 | 0.85 | TERT (0.66) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL9517250 | 0.85 | TERT (0.66) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL4188223 | 0.85 | TERT (0.66) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL8526011 | 0.85 | TERT (0.66) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL8150267 | 0.85 | TERT (0.66) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL9127461 | 0.85 | TERT (0.66) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL5077835 | 0.85 | TERT (0.66) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL422846 | 0.85 | TERT (0.66) | TERTPTPN1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313026-A1 | ACTIVE DELIVERY SYSTEM FORMULATIONS | Castle Beach, L.L.C. (US) | 2011-04-27 | — | — | EP | claimed |
| US-20100040565-A1 | ACTIVE DELIVERY SYSTEMS FORMULATIONS | Castle Beach, LLC (US) | 2010-02-18 | — | — | US | claimed |
| WO-2010019680-A1 | ACTIVE DELIVERY SYSTEM FORMULATIONS | HOMOLA ANDREW M (US) | 2010-02-18 | — | — | WO | claimed |
| EP-0805672-B1 | METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH | HOMOLA ANDREW M (US) | 2004-08-25 | — | — | EP | claimed |
| US-5665333-A | Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth | PROVSEAL LLC | 1997-09-09 | — | — | US | claimed |
| US-9833390-B2 | Dental device for inhibition of plaque, calculus and gingivitis | PROVSEAL LLC (US) | 2017-12-05 | — | — | US | disclosed |
| US-20170042773-A1 | Dental Device for Inhibition of Plaque, Calculus and Gingivitis | PROVSEAL LLC | 2017-02-16 | — | — | US | disclosed |
| EP-2313026-A1 | ACTIVE DELIVERY SYSTEM FORMULATIONS | Castle Beach, L.L.C. (US) | 2011-04-27 | — | — | EP | disclosed |
| US-20100040565-A1 | ACTIVE DELIVERY SYSTEMS FORMULATIONS | Castle Beach, LLC (US) | 2010-02-18 | — | — | US | disclosed |
| WO-2010019680-A1 | ACTIVE DELIVERY SYSTEM FORMULATIONS | HOMOLA ANDREW M (US) | 2010-02-18 | — | — | WO | disclosed |
| EP-0959872-B1 | METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH | FOUR STAR PARTNERS (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-1328184-A4 | MULTICOMPONENT BIODEGRADABLE BIOADHESIVE CONTROLLED RELEASE SYSTEM FOR ORAL CARE PRODUCTS | SALVONA LLC (US) | 2005-09-21 | — | — | EP | disclosed |
| EP-0805672-A4 | METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH | HOMOLA ANDREW M (US) | 1999-06-30 | — | — | EP | disclosed |
| US-5888480-A | COMPOSITION CONSISTING OF LECITHIN AND WAX BARRIER MATERIAL AS TOOTHPASTE OR COATED ON SOLID SUBSTRATE | FOUR STAR PARTNERS (US) | 1999-03-30 | — | — | US | disclosed |
| WO-1998002136-A9 | METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH | — | 1998-05-28 | — | — | WO | disclosed |
| EP-0805672-A1 | METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH | HOMOLA, Andrew M. (US) | 1997-11-12 | — | — | EP | disclosed |
| US-5665333-A | Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth | PROVSEAL LLC | 1997-09-09 | — | — | US | disclosed |
| WO-1996022078-A1 | METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH | HOMOLA ANDREW M (US) | 1996-07-25 | — | — | WO | disclosed |
| US-4196189-A | Dental and oral hygiene preparations | BLENDAX-WERKE R. SCHNEIDER (DE) | 1980-04-01 | — | — | US | disclosed |
| US-4169885-A | DENTAL AND ORAL HYGIENE PREPARATIONS | BLENDAX-WERKE R. SCHNEIDER GMBH & CO. (DE) | 1979-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100040565-A1 | ACTIVE DELIVERY SYSTEMS FORMULATIONS | LIPA, MMP7, CTSA | TERT 3873/4885PTPN1 1599/4885PPARG 2008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.