Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | HK1 | P19367 | 2/20 | 0.39 |
| ▸ | HK2 | P52789 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15504503 | 1.00 | MAPK1 (0.53) | MAPK1NOD2HK1HK2NPC1 | |
| SCHEMBL15508077 | 0.93 | MAPK1 (0.64) | MAPK1NOD2HK1HK2NPC1 | |
| SCHEMBL15504330 | 0.93 | MAPK1 (0.64) | MAPK1NOD2HK1HK2NPC1 | |
| SCHEMBL15514521 | 0.93 | MAPK1 (0.64) | MAPK1NOD2HK1HK2NPC1 | |
| SCHEMBL15513895 | 0.93 | MAPK1 (0.64) | MAPK1NOD2HK1HK2NPC1 | |
| SCHEMBL15514519 | 0.93 | MAPK1 (0.64) | MAPK1NOD2HK1HK2NPC1 | |
| SCHEMBL15504317 | 0.93 | MAPK1 (0.64) | MAPK1NOD2HK1HK2NPC1 | |
| SCHEMBL15514428 | 0.91 | MAPK1 (0.52) | MAPK1NOD2HK1HK2NPC1 | |
| SCHEMBL15504325 | 0.91 | MAPK1 (0.52) | MAPK1NOD2HK1HK2NPC1 | |
| SCHEMBL15504494 | 0.86 | MAPK1 (0.44) | MAPK1NOD2NPC1RAB9ALGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140073589-A1 | Amphetamine Prodrugs | SHIRE AG (CH) | 2014-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073589-A1 | Amphetamine Prodrugs | SLC6A2, SLC6A3, TAAR5 | MAPK1 3205/4885NOD2 3141/4885HK1 2779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.