Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.55 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28529684 | 0.83 | ACP1 (0.51) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL5141417 | 0.81 | MEN1 (0.71) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9670363 | 0.81 | ALDH1A1 (0.69) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL29748804 | 0.80 | MEN1 (0.65) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL333559 | 0.80 | MEN1 (0.65) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11763476 | 0.80 | KMT2A (0.59) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL733776 | 0.80 | EPHX2 (0.53) | MAPTALDH1A1HTTALOX5EPHX2 | |
| SCHEMBL8512871 | 0.79 | CYP3A4 (0.61) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10995578 | 0.79 | TSHR (0.64) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2777887 | 0.79 | GAA (0.66) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103601684-B | 5-arylseleno benzimidazoles compound and uses thereof | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-102070466-A | Preparation method of 5-chiorine-2-nitroaniline | JUNKAI TIANJIN CHEMICAL CO LTD | 2011-05-25 | — | — | CN | claimed |
| EP-1590332-B1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND THEIR DERIVATIVES. | UNIV DELHI (IN) | 2011-04-27 | — | — | EP | claimed |
| EP-1590332-A1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND ITS DERIVATIONS | University of Delhi (IN) | 2005-11-02 | — | — | EP | claimed |
| WO-2004063170-A1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND ITS DERIVATIONS | UNIVERSITY OF DELHI (IN) | 2004-07-29 | — | — | WO | claimed |
| CN-103601684-B | 5-arylseleno benzimidazoles compound and uses thereof | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-103601684-A | 5-arylselenobenzimidazole compound and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2014-02-26 | — | — | CN | disclosed |
| CN-102070466-A | Preparation method of 5-chiorine-2-nitroaniline | JUNKAI TIANJIN CHEMICAL CO LTD | 2011-05-25 | — | — | CN | disclosed |
| CN-102070466-A | Preparation method of 5-chiorine-2-nitroaniline | JUNKAI TIANJIN CHEMICAL CO LTD | 2011-05-25 | — | — | CN | disclosed |
| EP-1590332-B1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND THEIR DERIVATIVES. | UNIV DELHI (IN) | 2011-04-27 | — | — | EP | disclosed |
| EP-1590332-B1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND THEIR DERIVATIVES. | UNIV DELHI (IN) | 2011-04-27 | — | — | EP | disclosed |
| EP-1590332-A1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND ITS DERIVATIONS | University of Delhi (IN) | 2005-11-02 | — | — | EP | disclosed |
| EP-0147537-A1 | Phenylguanidines | SCHERING CORPORATION (US) | 1985-07-10 | — | — | EP | disclosed |
| WO-1985001283-A1 | PHENYLGUANIDINES | SCHERING CORP. (US) | 1985-03-28 | — | — | WO | disclosed |
| EP-0126294-A1 | New diphenyl ethers having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-11-28 | — | — | EP | disclosed |
| US-4420487-A | Diuretic and antihypertensive benzimidazoles | THE PURDUE FREDERICK COMPANY (US) | 1983-12-13 | — | — | US | disclosed |
| US-4258198-A | ANTHELMINTICS | SMITHKLINE CORPORATION (US) | 1981-03-24 | — | — | US | disclosed |
| US-4167569-A | ANTICOAGULANTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-09-11 | — | — | US | disclosed |
| US-4025638-A | ANTHELMINTICS | SMITHKLINE CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
| US-3969526-A | Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles | SMITHKLINE CORPORATION (US) | 1976-07-13 | — | — | US | disclosed |