Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20165835 | 0.93 | CYP3A4 (0.57) | CYP3A4EPHX1EPHX2MAPTNPSR1 | |
| SCHEMBL27546640 | 0.86 | HPGD (0.61) | CYP3A4MAPTALDH1A1ALOX15MEN1 | |
| SCHEMBL10995578 | 0.86 | TSHR (0.64) | MAPTNPSR1ALDH1A1MEN1NPC1 | |
| SCHEMBL11348484 | 0.86 | MEN1 (0.61) | CYP3A4MAPTALDH1A1ALOX15MEN1 | |
| SCHEMBL5491596 | 0.83 | ALDH1A1 (0.60) | MAPTNPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL11763476 | 0.81 | KMT2A (0.59) | MAPTNPSR1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL4004069 | 0.80 | CYP3A4 (0.69) | CYP3A4EPHX1EPHX2MAPTNPSR1 | |
| SCHEMBL5494871 | 0.79 | MAPT (0.45) | CYP3A4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7088341 | 0.79 | MEN1 (0.52) | CYP3A4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1551584 | 0.79 | MAPT (0.57) | EPHX2MAPTNPSR1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091978-A1 | A PROCESS FOR THE PREPARATION OF 2-NITRO-4,5- DICHLOROACETANILIDE | AMOGH CHEMICALS PVT. LTD (IN) | 2018-05-24 | — | — | WO | claimed |
| WO-2018091978-A1 | A PROCESS FOR THE PREPARATION OF 2-NITRO-4,5- DICHLOROACETANILIDE | AMOGH CHEMICALS PVT. LTD (IN) | 2018-05-24 | — | — | WO | disclosed |
| WO-2018091978-A1 | A PROCESS FOR THE PREPARATION OF 2-NITRO-4,5- DICHLOROACETANILIDE | AMOGH CHEMICALS PVT. LTD (IN) | 2018-05-24 | — | — | WO | disclosed |
| US-20130303781-A1 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2013-11-14 | — | — | US | disclosed |
| EP-2642995-A2 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | Sequent Scientific Ltd. (IN) | 2013-10-02 | — | — | EP | disclosed |
| CN-103012277-A | Process for synthesizing benzimidazole derivative | ZHANG WANYING | 2013-04-03 | — | — | CN | disclosed |
| WO-2012070068-A2 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |
| CN-102452985-A | Synthesis process of benzimidazole derivative | YIHE TONG | 2012-05-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303781-A1 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | NIT2, CA3, TET3 | CYP3A4 375/4885EPHX1 2525/4885EPHX2 1878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.