SCHEMBL15516635

SCHEMBL15516635

[CH2]CCc1cc(Cl)c(Cl)c(C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.41
NOTUM Q6P988 1/20 0.37
DAO P14920 1/20 0.33
GPR84 Q9NQS5 1/20 0.32
PYCR1 P32322 1/20 0.32
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15516910 0.90 IDO1 (0.41) IDO1NOTUMGPR84PYCR1
SCHEMBL15516526 0.85 NOTUM (0.42) IDO1NOTUMDAOGPR84PYCR1
SCHEMBL9293760 0.80 ALDH1A1 (0.41) IDO1LMNAMAPT
SCHEMBL16571434 0.78 IDO1 (0.62) IDO1NOTUMDAOGPR84PYCR1
SCHEMBL16571747 0.78 DAO (0.52) IDO1NOTUMDAOGPR84PYCR1
SCHEMBL2554068 0.77 IDO1 (0.40) IDO1NOTUMDAOGPR84PYCR1
SCHEMBL15516766 0.74 IDO1 (0.39) IDO1NOTUMPYCR1
SCHEMBL15517336 0.71 PNMT (0.31) IDO1
SCHEMBL15517298 0.70 NOTUM (0.42) IDO1NOTUM
SCHEMBL15517328 0.69 PNMT (0.32) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2887802-A2 METHODS OF SOIL PEST CONTROL Syngenta Participations AG (CH) 2015-07-01 EP disclosed
WO-2014029706-A2 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029710-A2 METHODS OF SOIL PEST CONTROL SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029708-A1 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029707-A1 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014019609-A1 METHODS OF PEST CONTROL IN SOYBEAN SYNGENTA PARTICIPATIONS AG (CH) 2014-02-06 WO disclosed