SCHEMBL15516779

SCHEMBL15516779

Clc1cc(C2CCC2)cc(Cl)c1I

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
SLC6A3 Q01959 2/20 0.39
KCNH2 Q12809 2/20 0.39
CYP2D6 P10635 1/20 0.39
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15517454 0.90 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL15516914 0.83 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL15517104 0.79 SLC6A2 (0.38) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL3781520 0.77 TSHR (0.37) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL15562086 0.75 TSHR (0.42) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL2407 0.74 SLC6A2 (0.65) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL8579966 0.73 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL5581517 0.73 TSHR (0.49) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL778085 0.73 HDAC8 (0.43) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL15516459 0.72 ALDH1A1 (0.43) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2887802-A2 METHODS OF SOIL PEST CONTROL Syngenta Participations AG (CH) 2015-07-01 EP disclosed
WO-2014029710-A2 METHODS OF SOIL PEST CONTROL SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029707-A1 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029708-A1 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029706-A2 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014019609-A1 METHODS OF PEST CONTROL IN SOYBEAN SYNGENTA PARTICIPATIONS AG (CH) 2014-02-06 WO disclosed