SCHEMBL5581517

SCHEMBL5581517

Oc1c(Cl)cc(C2CCCCC2)cc1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.49
CYP2D6 P10635 2/20 0.49
CYP2C9 P11712 2/20 0.49
HSD17B10 Q99714 4/20 0.42
ALDH1A1 P00352 3/20 0.42
TTR P02766 2/20 0.42
CYP3A4 P08684 1/20 0.42
RECQL P46063 1/20 0.42
ACMSD Q8TDX5 2/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
KCNH2 Q12809 2/20 0.41
THRB P10828 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
ALOX15 P16050 2/20 0.38
ALOX12 P18054 2/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19031706 0.87 CYP2D6 (0.39) TSHRCYP2D6CYP2C9HSD17B10ALDH1A1
Diethanolamine SCHEMBL11576306 0.85 TSHR (0.42) TSHRCYP2D6CYP2C9HSD17B10ALDH1A1
SCHEMBL27734028 0.82 CYP2C9 (0.38) TSHRCYP2D6CYP2C9ALDH1A1ACMSD
SCHEMBL27579601 0.82 GABRA1 (0.43) TSHRCYP2D6CYP2C9ACMSDSLC6A2
SCHEMBL11231372 0.82 ACMSD (0.58) HSD17B10ALDH1A1TTRACMSDSMN1; SMN2
SCHEMBL28807818 0.82 CYP2D6 (0.40) TSHRCYP2D6CYP2C9ACMSDSLC6A2
SCHEMBL29567430 0.82 CYP2C9 (0.36) TSHRCYP2D6CYP2C9HSD17B10ALDH1A1
SCHEMBL26659466 0.82 CYP2C9 (0.36) TSHRCYP2D6CYP2C9HSD17B10ALDH1A1
Benzylamine SCHEMBL11504080 0.81 CYP2D6 (0.42) TSHRCYP2D6CYP2C9CYP3A4ACMSD
SCHEMBL19031723 0.80 PRKAB2 (0.39) ALDH1A1ACMSDHDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115443299-B Polysiloxane-polycarbonate copolymers utilizing hydroxyl-terminated polysiloxane mixtures and methods of making the same 株式会社三养社 2024-05-10 CN disclosed
CN-117545793-A Hydroxyphenyl-terminated polysiloxane, polysiloxane-polycarbonate copolymer having excellent transparency and improved flame retardancy comprising the same as a repeating unit, and method for preparing the same 株式会社三养社 2024-02-09 CN disclosed
CN-112566981-B Polycarbonate resin composition for 3D printing and filament for 3D printing comprising the same 株式会社三养社 2023-10-10 CN disclosed
CN-116635477-A Polycarbonate resin composition for 3D printing having excellent shape retention and interfacial adhesion, and 3D printing particle and filament comprising same 株式会社三养社 2023-08-22 CN disclosed
CN-113614178-B Thermoplastic resin composition and molded article 株式会社钟化 2023-06-16 CN disclosed
CN-112313277-B Polyethylene with polycarbonate-siloxane for improved environmental stress cracking resistance SABIC环球技术有限责任公司 2023-06-13 CN disclosed
CN-115443299-A Polysiloxane-polycarbonate copolymers utilizing hydroxyl-terminated polysiloxane mixtures and methods of making the same 株式会社三养社 2022-12-06 CN disclosed
CN-115428128-A Hollow microspheres 株式会社德山 2022-12-02 CN disclosed
CN-111630107-B Molded body 三菱瓦斯化学株式会社 2022-11-15 CN disclosed
CN-114728255-A Microspheres containing ionic groups and method for producing same 株式会社德山 2022-07-08 CN disclosed
WO-2019198675-A1 URETHANE RESIN USING POLYROTAXANE, AND PAD FOR POLISHING 株式会社トクヤマ 2019-10-17 WO disclosed
EP-1778787-B1 ANTI-STATIC FLAME RETARDANT RESIN COMPOSITION AND METHODS FOR MANUFACTURE THEREOF SABIC INNOVATIVE PLASTICS IP (NL) 2012-11-21 EP disclosed
CN-101472994-A Polycarbonate compositions and articles formed therefrom GEN ELECTRIC (NL) 2009-07-01 CN disclosed
CN-101400763-A Halogen-free polycarbonate compositions and articles formed therefrom SABIC INNOVATIVE PLASTICS IP (NL) 2009-04-01 CN disclosed
EP-1778787-A1 ANTI-STATIC FLAME RETARDANT RESIN COMPOSITION AND METHODS FOR MANUFACTURE THEREOF The General Electric Company (US) 2007-05-02 EP disclosed
US-7071285-B2 Aromatic polycarbonate resin, electrophotographic photoconductor, process cartridge, and electrophotographic image forming method and apparatus RICOH COMPANY, LTD. (JP) 2006-07-04 US disclosed
WO-2006020221-A1 ANTI-STATIC FLAME RETARDANT RESIN COMPOSITION AND METHODS FOR MANUFACTURE THEREOF GENERAL ELECTRIC COMPANY (US) 2006-02-23 WO disclosed
US-20060020060-A1 Anti-static flame retardant resin composition and methods for manufacture thereof GENERAL ELECTRIC COMPANY 2006-01-26 US disclosed
US-20050003287-A1 Aromatic polycarbonate resin, electrophotographic photoconductor, process cartridge, and electrophotographic image forming method and apparatus RICOH COMPANY, LTD. (JP) 2005-01-06 US disclosed
CN-1383450-A Antibody molecule with specificity to human tumor necrosis factor alpha and application thereof CELLTECH R&D LTD (GB) 2002-12-04 CN disclosed