SCHEMBL15517152

SCHEMBL15517152

[CH2]CCc1ccc(F)c(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.45
PNMT P11086 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45
PIK3CA P42336 1/20 0.41
SIGMAR1 Q99720 3/20 0.38
MEN1 O00255 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
PLA2G1B P04054 1/20 0.38
GAA P10253 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
MAOB P27338 1/20 0.37
RPA1 P27694 1/20 0.37
SOS1 Q07889 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16954102 0.88 DAO (0.43) DAOPNMTTAAR1PIK3CASIGMAR1
SCHEMBL10823078 0.83 PNMT (0.45) PNMTTAAR1SIGMAR1MAPT
SCHEMBL151278 0.83 PIK3CA (0.44) DAOPNMTTAAR1PIK3CAMEN1
SCHEMBL23850015 0.81 TAAR1 (0.47) DAOPNMTTAAR1PIK3CASIGMAR1
SCHEMBL793707 0.81 TAAR1 (0.69) DAOPNMTTAAR1SIGMAR1MAPT
SCHEMBL3565937 0.80 PNMT (0.61) PNMTTAAR1SIGMAR1MEN1MAPT
SCHEMBL7092270 0.80 DAO (0.44) DAOTAAR1HDAC1HDAC6MAOB
SCHEMBL3264645 0.79 MAPT (0.47) DAOPNMTTAAR1PIK3CAMEN1
SCHEMBL530440 0.79 DAO (0.45) DAOPNMTTAAR1PIK3CASIGMAR1
SCHEMBL17552730 0.79 TAAR1 (0.45) DAOPNMTTAAR1PIK3CASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed
EP-2887802-A2 METHODS OF SOIL PEST CONTROL Syngenta Participations AG (CH) 2015-07-01 EP disclosed
WO-2014029706-A2 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029707-A1 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029710-A2 METHODS OF SOIL PEST CONTROL SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029708-A1 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014019609-A1 METHODS OF PEST CONTROL IN SOYBEAN SYNGENTA PARTICIPATIONS AG (CH) 2014-02-06 WO disclosed
CN-101272781-A Novel 1-aryl-3-azabicyclo [3.1.0] hexanes: processes for their preparation and their use for the treatment of neuropsychiatric disorders DOV PHARMACEUTICAL INC (US) 2008-09-24 CN disclosed
CN-1291958-C Naphthacridine derivative and liquid crystal composite containing it DAINIPPON INK CHEMICAL IND CO (JP) 2006-12-27 CN disclosed