Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519989 | 0.90 | ALDH1A1 (0.45) | ALDH1A1POLBLMNASCN9ASMN1; SMN2 | |
| SCHEMBL19750044 | 0.86 | ALDH1A1 (0.45) | ALDH1A1POLBLMNASCN9ASMN1; SMN2 | |
| SCHEMBL15517248 | 0.86 | ALDH1A1 (0.42) | ALDH1A1POLBLMNASCN9ASMN1; SMN2 | |
| SCHEMBL15517487 | 0.84 | ALDH1A1 (0.48) | ALDH1A1POLBLMNASCN9ASMN1; SMN2 | |
| SCHEMBL15516042 | 0.83 | GRN (0.49) | ALDH1A1POLBLMNASCN9ASMN1; SMN2 | |
| SCHEMBL20015660 | 0.81 | SCN9A (0.42) | ALDH1A1POLBLMNASCN9ASMN1; SMN2 | |
| SCHEMBL20028223 | 0.79 | KMT2A (0.53) | ALDH1A1POLBLMNASCN9ASMN1; SMN2 | |
| SCHEMBL15519124 | 0.78 | ALDH1A1 (0.52) | ALDH1A1POLBLMNASMN1; SMN2KMT2A | |
| SCHEMBL20028218 | 0.78 | KMT2A (0.52) | ALDH1A1POLBLMNASCN9ASMN1; SMN2 | |
| SCHEMBL20027770 | 0.78 | KMT2A (0.52) | ALDH1A1POLBLMNASCN9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796742-B2 | Kinase inhibitors | RESPIVERT LIMITED (GB) | 2017-10-24 | — | — | US | disclosed |
| EP-2890460-B1 | KINASE INHIBITORS | RESPIVERT LTD (GB) | 2017-02-22 | — | — | EP | disclosed |
| US-20160340375-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2016-11-24 | — | — | US | disclosed |
| US-20150210722-A1 | KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2015-07-30 | — | — | US | disclosed |
| EP-2890460-A1 | KINASE INHIBITORS | Respivert Limited (GB) | 2015-07-08 | — | — | EP | disclosed |
| WO-2014033446-A1 | KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2014-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210722-A1 | KINASE INHIBITORS | SYK, SRC, LYN | ALDH1A1 2702/4885POLB 3918/4885LMNA 2738/4885 |
| US-20160340375-A1 | KINASE INHIBITORS | SYK, LYN, BTK | ALDH1A1 2639/4885POLB 3978/4885LMNA 2949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.