Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15517521 | 0.88 | ALDH1A1 (0.51) | ALDH1A1POLBLMNACA1CA2 | |
| SCHEMBL16931589 | 0.85 | ALDH1A1 (0.48) | ALDH1A1POLBLMNAKMT2AUSP2 | |
| SCHEMBL1877271 | 0.85 | SMN1; SMN2 (0.52) | ALDH1A1POLBLMNACA12CA1 | |
| SCHEMBL16990177 | 0.82 | ALDH1A1 (0.46) | ALDH1A1POLBLMNAKMT2AUSP2 | |
| SCHEMBL15516831 | 0.82 | POLB (0.45) | ALDH1A1POLBLMNAKMT2AUSP2 | |
| SCHEMBL16990181 | 0.81 | ALDH1A1 (0.60) | ALDH1A1POLBLMNACA9KMT2A | |
| SCHEMBL15519989 | 0.79 | ALDH1A1 (0.45) | ALDH1A1POLBLMNAKMT2AHTT | |
| SCHEMBL15517374 | 0.79 | ALDH1A1 (0.58) | ALDH1A1POLBLMNACA9KMT2A | |
| SCHEMBL16990180 | 0.79 | ALDH1A1 (0.57) | ALDH1A1POLBLMNACA9KMT2A | |
| SCHEMBL15517367 | 0.78 | ALDH1A1 (0.44) | ALDH1A1POLBLMNAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9783556-B2 | Kinase inhibitors | RESPIVERT LIMITED (GB) | 2017-10-10 | — | — | US | disclosed |
| EP-2890701-B1 | KINASE INHIBITORS | RESPIVERT LTD (GB) | 2017-03-29 | — | — | EP | disclosed |
| US-20150225427-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2015-08-13 | — | — | US | disclosed |
| EP-2890701-A1 | KINASE INHIBITORS | Respivert Limited (GB) | 2015-07-08 | — | — | EP | disclosed |
| WO-2014033449-A1 | KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2014-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225427-A1 | KINASE INHIBITORS | SYK, LYN, BTK | ALDH1A1 2547/4885POLB 3759/4885LMNA 2341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.