Cystine

Cystine

SCHEMBL15517596

CC(O)C(N)C(=O)O.NC(CSSCC(N)C(=O)O)C(=O)O

nearest known ligand 0.43

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.43
NOS2 P35228 3/20 0.42
NOS1 P29475 2/20 0.42
NOS3 P29474 1/20 0.42
SLC1A3 P43003 3/20 0.39
SLC1A2 P43004 3/20 0.39
SLC1A1 P43005 2/20 0.39
KIF11 P52732 4/20 0.39
ARG1 P05089 1/20 0.39
ARG2 P78540 1/20 0.39
BHMT Q93088 2/20 0.38
BHMT2 Q9H2M3 1/20 0.38
GLO1 Q04760 1/20 0.37
PTGS1 P23219 1/20 0.37
SLC7A11 Q9UPY5 1/20 0.37
GRIK1 P39086 1/20 0.36
GRIK2 Q13002 1/20 0.36
GRM1 Q13255 1/20 0.36
GRM2 Q14416 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cystine SCHEMBL10776039 1.00 SLC7A5 (0.43) SLC7A5NOS2NOS1NOS3SLC1A3
Cystine SCHEMBL10776054 1.00 SLC7A5 (0.43) SLC7A5NOS2NOS1NOS3SLC1A3
Cystine SCHEMBL10776045 1.00 SLC7A5 (0.43) SLC7A5NOS2NOS1NOS3SLC1A3
Cystine SCHEMBL9051990 0.91 PTGS1 (0.53) SLC7A5NOS2NOS1NOS3SLC1A3
Cystine SCHEMBL28360714 0.86 SLC7A5 (0.62) SLC7A5NOS2NOS1NOS3SLC1A3
Cystine SCHEMBL28475009 0.85 ARG1 (0.48) SLC7A5NOS2NOS1NOS3SLC1A3
Cystine SCHEMBL28475011 0.85 ARG1 (0.48) SLC7A5NOS2NOS1NOS3SLC1A3
Cystine SCHEMBL28213243 0.83 SLC7A5 (0.50) SLC7A5NOS2NOS1NOS3SLC1A3
Cystine SCHEMBL10224 0.82 PTGS1 (0.50) SLC7A5NOS2NOS1NOS3SLC1A3
Cystine SCHEMBL8332360 0.82 PTGS1 (0.50) SLC7A5NOS2NOS1NOS3SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2890817-A1 METHOD FOR PARTIAL DEGRADATION OF GLUTEN Giuliani S.p.A. (IT) 2015-07-08 EP disclosed
WO-2014033765-A1 METHOD FOR PARTIAL DEGRADATION OF GLUTEN GIULIANI S.P.A. (IT) 2014-03-06 WO disclosed