Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.51 |
| ▸ | MEN1 | O00255 | 11/20 | 0.51 |
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15516799 | 0.78 | G6PD (0.45) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL5447146 | 0.78 | KMT2A (0.57) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL2469901 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL2469833 | 0.74 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11973409 | 0.71 | KMT2A (0.55) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL10915347 | 0.71 | MAPT (0.61) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL21816812 | 0.71 | MAPT (0.61) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL12154377 | 0.70 | MEN1 (0.57) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL20554098 | 0.70 | GAA (0.73) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL29800743 | 0.70 | MAPT (0.47) | ALDH1A1KMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796742-B2 | Kinase inhibitors | RESPIVERT LIMITED (GB) | 2017-10-24 | — | — | US | disclosed |
| US-9732063-B2 | Kinase inhibitors | RESPIVERT LIMITED (GB) | 2017-08-15 | — | — | US | disclosed |
| EP-2890460-B1 | KINASE INHIBITORS | RESPIVERT LTD (GB) | 2017-02-22 | — | — | EP | disclosed |
| US-20160340375-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2016-11-24 | — | — | US | disclosed |
| EP-2925742-B1 | KINASE INHIBITORS | RESPIVERT LTD (GB) | 2016-10-26 | — | — | EP | disclosed |
| US-20150329523-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2015-11-19 | — | — | US | disclosed |
| EP-2925742-A1 | KINASE INHIBITORS | Respivert Limited (GB) | 2015-10-07 | — | — | EP | disclosed |
| US-20150210722-A1 | KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2015-07-30 | — | — | US | disclosed |
| EP-2890460-A1 | KINASE INHIBITORS | Respivert Limited (GB) | 2015-07-08 | — | — | EP | disclosed |
| WO-2014076484-A1 | KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2014-05-22 | — | — | WO | disclosed |
| WO-2014033446-A1 | KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2014-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210722-A1 | KINASE INHIBITORS | SYK, SRC, LYN | ALDH1A1 2702/4885KMT2A 2457/4885MEN1 4580/4885 |
| US-20160340375-A1 | KINASE INHIBITORS | SYK, LYN, BTK | ALDH1A1 2639/4885KMT2A 2476/4885MEN1 4489/4885 |
| US-20150329523-A1 | KINASE INHIBITORS | SYK, SRC, BTK | ALDH1A1 4202/4885KMT2A 3728/4885MEN1 4570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.