Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | CASP7 | P55210 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27966123 | 0.98 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1ARALOX15 | |
| SCHEMBL3470934 | 0.96 | ALDH1A1 (0.47) | ALDH1A1KDM4EL3MBTL1ARALOX15 | |
| Hydrochloric Acid SCHEMBL27634037 | 0.83 | ADRB1 (0.61) | ALDH1A1KDM4EMAPTLMNAADRB1 | |
| SCHEMBL829177 | 0.83 | AR (0.65) | ALDH1A1KDM4EL3MBTL1ARGAA | |
| SCHEMBL2785503 | 0.82 | DRD4 (0.46) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL1878340 | 0.81 | ALDH1A1 (0.69) | ALDH1A1KDM4EL3MBTL1ARALOX15 | |
| SCHEMBL7528396 | 0.81 | AR (0.62) | ALDH1A1KDM4EL3MBTL1ARGAA | |
| SCHEMBL31388194 | 0.81 | AR (0.62) | ALDH1A1KDM4EL3MBTL1ARGAA | |
| SCHEMBL7524105 | 0.81 | AR (0.62) | ALDH1A1KDM4EL3MBTL1ARGAA | |
| SCHEMBL1660394 | 0.81 | AR (0.62) | ALDH1A1KDM4EL3MBTL1ARGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364314-B1 | MODULATORS OF TOLL-LIKE RECEPTORS | GILEAD SCIENCES INC (US) | 2014-03-12 | — | — | EP | disclosed |