Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519445 | 1.00 | CD274 (0.41) | CD274RXRARXRBRXRGCYP4F2 | |
| SCHEMBL20516929 | 0.85 | CD274 (0.41) | CD274RXRARXRBRXRGCYP4F2 | |
| SCHEMBL15603525 | 0.81 | CD274 (0.40) | CD274RXRARXRBRXRGCYP4F2 | |
| SCHEMBL28361826 | 0.79 | CD274 (0.41) | CD274RXRARXRBRXRGCYP4F2 | |
| SCHEMBL22816843 | 0.78 | CD274 (0.35) | CD274CYP4F2CYP4A11IDH1MEN1 | |
| SCHEMBL22236106 | 0.77 | CD274 (0.44) | CD274RXRARXRBRXRGCYP4F2 | |
| SCHEMBL20519313 | 0.74 | NPC1 (0.43) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL20524397 | 0.74 | NPC1 (0.43) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL31338368 | 0.74 | RXRA (0.45) | CD274RXRARXRBRXRGCYP4F2 | |
| SCHEMBL20517556 | 0.74 | CYP4F2 (0.46) | RXRARXRBRXRGCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2014-03-20 | — | — | US | disclosed |
| EP-2708537-A1 | HETEROAROMATIC RING DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-03-19 | — | — | EP | disclosed |
| US-20090036357-A1 | Azapeptide derivatives | CONCERT PHARMACEUTICALS, INC. (US) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036357-A1 | Azapeptide derivatives | SAMHD1, ENTPD5, DNPEP | CD274 1373/4885RXRA 4734/4885RXRB 4775/4885 |
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | HCRTR2, HCRTR1, HTT | CD274 611/4885RXRA 1208/4885RXRB 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.