SCHEMBL1551949

SCHEMBL1551949

CCCCc1c(N=C=O)cccc1N=C=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.57
GABRA1 P14867 2/20 0.44
GABRB2 P47870 2/20 0.44
TRPA1 O75762 1/20 0.38
KCNH2 Q12809 2/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 4/20 0.34
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 3/20 0.34
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
HTT P42858 2/20 0.32
MAPK1 P28482 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15005154 0.93 CYP3A4 (0.53) CYP3A4GABRA1GABRB2KCNH2GPR84
SCHEMBL2346860 0.90 CYP3A4 (0.50) CYP3A4GABRA1GABRB2TRPA1CYP2D6
SCHEMBL28260103 0.89 CYP3A4 (0.55) CYP3A4GABRA1GABRB2TRPA1CYP2C9
SCHEMBL10971614 0.86 CYP3A4 (0.46) CYP3A4GABRA1GABRB2TRPA1CYP2D6
SCHEMBL10965705 0.85 CYP3A4 (0.45) CYP3A4GABRA1GABRB2TRPA1CYP2D6
SCHEMBL11455741 0.84 GABRA1 (0.49) CYP3A4GABRA1GABRB2KCNH2GPR84
SCHEMBL3920104 0.83 CYP3A4 (0.59) CYP3A4GABRA1GABRB2TRPA1CYP2D6
SCHEMBL10965192 0.81 CYP3A4 (0.45) CYP3A4GABRA1GABRB2KCNH2CYP2D6
SCHEMBL10967508 0.80 CYP3A4 (0.44) CYP3A4GABRA1GABRB2KCNH2KDM4E
SCHEMBL10965239 0.80 CYP3A4 (0.44) CYP3A4GABRA1GABRB2KCNH2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105778026-B Carbodiimides quasi-oligomer containing steric hindrance and its preparation method and application 上海华峰新材料研发科技有限公司 2018-11-20 CN disclosed
EP-2313209-A1 AMBIENT CURE SOLVENT-BASED COATINGS FOR WRITABLE-ERASABLE SURFACES IdeaPaint, Inc. (US) 2011-04-27 EP disclosed
WO-2010009384-A1 AMBIENT CURE SOLVENT-BASED COATINGS FOR WRITABLE-ERASABLE SURFACES IDEA PAINT INC. (US) 2010-01-21 WO disclosed
EP-1162949-A4 URETHANE SURFACTANTS AND THEIR USE IN PERSONAL CARE FORMULATIONS ALZO INC (US) 2003-05-07 EP disclosed
EP-1162949-A1 URETHANE SURFACTANTS AND THEIR USE IN PERSONAL CARE FORMULATIONS Alzo, Inc. (US) 2001-12-19 EP disclosed
WO-2000056285-A1 URETHANE SURFACTANTS AND THEIR USE IN PERSONAL CARE FORMULATIONS ALZO, INC. (US) 2000-09-28 WO disclosed