Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 13/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 5/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519636 | 0.82 | DHODH (0.70) | DHODHPARP1 | |
| SCHEMBL15515091 | 0.79 | PARP1 (0.65) | DHODHPARP1PARP2 | |
| SCHEMBL15520334 | 0.79 | PKN1 (0.63) | DHODHPARP1 | |
| SCHEMBL6585185 | 0.76 | HPSE (0.44) | DHODHHPSEPARP1MGAMGAA | |
| SCHEMBL7861249 | 0.74 | PARP1 (0.53) | DHODHHPSEPARP1 | |
| SCHEMBL7859132 | 0.73 | PARP1 (0.52) | DHODHHPSEPARP1 | |
| SCHEMBL7853256 | 0.73 | PARP1 (0.65) | DHODHHPSEPARP1 | |
| SCHEMBL7860364 | 0.70 | PARP1 (0.69) | DHODHPARP1 | |
| SCHEMBL7759237 | 0.70 | AURKA (0.54) | DHODHHPSEPARP1 | |
| SCHEMBL7864193 | 0.70 | PARP1 (0.68) | DHODHPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892345-A1 | USE OF SUBSTITUTED 2-AMIDOBENZIMIDAZOLES, 2-AMIDOBENZOXAZOLES AND 2-AMIDOBENZOTHIAZOLES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | Bayer CropScience AG (DE) | 2015-07-15 | — | — | EP | disclosed |
| WO-2014037340-A1 | USE OF SUBSTITUTED 2-AMIDOBENZIMIDAZOLES, 2-AMIDOBENZOXAZOLES AND 2-AMIDOBENZOTHIAZOLES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2014-03-13 | — | — | WO | disclosed |