Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 11/20 | 0.47 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517783 | 0.95 | SCD (0.52) | SCDDCTPP1CYP2C9CYP2C19HTR2B | |
| SCHEMBL517077 | 0.88 | SCD (0.53) | SCDDCTPP1 | |
| SCHEMBL7936680 | 0.85 | SCD (0.53) | SCDDCTPP1CYP2C9CYP2C19HTR2B | |
| Trifluoroacetic Acid SCHEMBL518378 | 0.83 | SCD (0.51) | SCDDCTPP1CYP2C9CYP2C19HTR2B | |
| SCHEMBL10036776 | 0.83 | P2RX7 (0.44) | SCDDCTPP1HTR2B | |
| SCHEMBL518648 | 0.81 | SCD (0.57) | SCDDCTPP1 | |
| SCHEMBL517909 | 0.81 | SCD (0.51) | SCDDCTPP1CYP2C9CYP2C19HTR2B | |
| SCHEMBL7933451 | 0.81 | SCD (0.43) | SCDDCTPP1 | |
| SCHEMBL10036775 | 0.80 | SCD (0.53) | SCDDCTPP1CYP2C9CYP2C19HTR2B | |
| Trifluoroacetic Acid SCHEMBL518067 | 0.80 | SCD (0.41) | SCDDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673917-B2 | 2-heteroaryl-pyrrolo [3,4-C]pyrrole derivatives, and use thereof as SCD inhibitors | SANOFI (FR) | 2014-03-18 | — | — | US | disclosed |