Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519787 | 0.88 | SCD (0.47) | SCDDCTPP1 | |
| SCHEMBL1766107 | 0.86 | SCD (0.69) | SCDDCTPP1 | |
| SCHEMBL517783 | 0.80 | SCD (0.52) | SCDDCTPP1 | |
| SCHEMBL1922734 | 0.80 | SCD (0.48) | SCDDCTPP1 | |
| SCHEMBL518633 | 0.79 | CYP2C9 (0.53) | SCDDCTPP1 | |
| SCHEMBL7936680 | 0.79 | SCD (0.53) | SCDDCTPP1 | |
| SCHEMBL10036775 | 0.79 | SCD (0.53) | SCDDCTPP1 | |
| SCHEMBL1922946 | 0.79 | SCD (0.47) | SCDDCTPP1 | |
| SCHEMBL15579416 | 0.79 | SCD (0.48) | SCD | |
| SCHEMBL10036776 | 0.78 | P2RX7 (0.44) | SCDDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328898-B1 | 2-HETEROARYL-PYRROLO[3,4-C]PYRROLE DERIVATIVES AND THEIR USE AS SCD INHIBITORS | SANOFI SA (FR) | 2014-12-24 | — | — | EP | disclosed |
| EP-2328898-B1 | 2-HETEROARYL-PYRROLO[3,4-C]PYRROLE DERIVATIVES AND THEIR USE AS SCD INHIBITORS | SANOFI SA (FR) | 2014-12-24 | — | — | EP | disclosed |
| US-8673917-B2 | 2-heteroaryl-pyrrolo [3,4-C]pyrrole derivatives, and use thereof as SCD inhibitors | SANOFI (FR) | 2014-03-18 | — | — | US | disclosed |
| US-8673917-B2 | 2-heteroaryl-pyrrolo [3,4-C]pyrrole derivatives, and use thereof as SCD inhibitors | SANOFI (FR) | 2014-03-18 | — | — | US | disclosed |
| US-8673917-B2 | 2-heteroaryl-pyrrolo [3,4-C]pyrrole derivatives, and use thereof as SCD inhibitors | SANOFI (FR) | 2014-03-18 | — | — | US | disclosed |
| US-20120028986-A1 | 2-HETEROARYL-PYRROLO [3,4-C]PYRROLE DERIVATIVES, AND USE THEREOF AS SCD INHIBITORS | SANOFI-AVENTIS (FR) | 2012-02-02 | — | — | US | disclosed |
| US-20120028986-A1 | 2-HETEROARYL-PYRROLO [3,4-C]PYRROLE DERIVATIVES, AND USE THEREOF AS SCD INHIBITORS | SANOFI-AVENTIS (FR) | 2012-02-02 | — | — | US | disclosed |
| US-20120028986-A1 | 2-HETEROARYL-PYRROLO [3,4-C]PYRROLE DERIVATIVES, AND USE THEREOF AS SCD INHIBITORS | SANOFI-AVENTIS (FR) | 2012-02-02 | — | — | US | disclosed |
| EP-2328898-A1 | 2-HETEROARYL-PYRROLO [3, 4-C]PYRROLE DERIVATIVES AND THE USE THEREOF AS SCD INHIBITORS | Sanofi-aventis (FR) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010028761-A1 | 2-HETEROARYL-PYRROLO [3, 4-C]PYRROLE DERIVATIVES AND THE USE THEREOF AS SCD INHIBITORS | SANOFI-AVENTIS (FR) | 2010-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028986-A1 | 2-HETEROARYL-PYRROLO [3,4-C]PYRROLE DERIVATIVES, AND USE THEREOF AS SCD INHIBITORS | SCD, SCD5, PC | SCD 1/4885DCTPP1 1982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.