Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL474528 | 0.92 | GPR55 (0.33) | GPR55ALDH1A1MALT1KMOHRH3 | |
| SCHEMBL12164282 | 0.92 | GPR55 (0.33) | GPR55ALDH1A1MALT1KMOHRH3 | |
| SCHEMBL15580702 | 0.90 | GPR55 (0.33) | GPR55 | |
| SCHEMBL12164280 | 0.89 | GPR55 (0.34) | GPR55MALT1 | |
| SCHEMBL474356 | 0.89 | GPR55 (0.34) | GPR55MALT1 | |
| SCHEMBL12164240 | 0.89 | HRH3 (0.38) | GPR55ALDH1A1HRH3 | |
| SCHEMBL12164254 | 0.89 | GPR55 (0.33) | GPR55ALDH1A1MALT1KMOHRH3 | |
| SCHEMBL474020 | 0.89 | HRH3 (0.38) | GPR55ALDH1A1HRH3 | |
| SCHEMBL474532 | 0.89 | GPR55 (0.33) | GPR55ALDH1A1MALT1KMOHRH3 | |
| SCHEMBL12163916 | 0.87 | CMA1 (0.33) | GPR55ALDH1A1MALT1KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411365-B1 | 2,3-DIARYL- OR HETEROARYL-SUBSTITUTED 1,1,1-TRIFLUORO-2-HYDROXYPROPYL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2014-03-19 | — | — | EP | claimed |