SCHEMBL1552228

SCHEMBL1552228

CCOC(CO)CCOCCO

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
TSHR P16473 2/20 0.42
MAPK1 P28482 1/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
THRB P10828 1/20 0.38
HTT P42858 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9446799 0.81 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL14463127 0.80
SCHEMBL9622199 0.80
SCHEMBL28039444 0.78 THRB (0.32) ALDH1A1THRB
SCHEMBL13319641 0.78 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1MEN1KMT2A
2-Methoxyethanol SCHEMBL6031678 0.78 ALDH1A1 (0.34) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL6694563 0.78 TSHR (0.50) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL11191176 0.78 MEN1 (0.45) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL9599216 0.77 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL25779343 0.77 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8202676-B2 Toner for developing electrostatic latent image, and image forming method using the toner RICOH COMPANY, LIMITED (JP) 2012-06-19 US disclosed
EP-2078986-B1 Toner for developing electrostatic latent image, and image forming method using the toner RICOH CO LTD (JP) 2011-04-27 EP disclosed
EP-2078986-A1 Toner for developing electrostatic latent image, and image forming method using the toner Ricoh Company, Ltd. (JP) 2009-07-15 EP disclosed
US-20090176169-A1 TONER FOR DEVELOPING ELECTROSTATIC LATENT IMAGE, AND IMAGE FORMING METHOD USING THE TONER RICOH COMPANY LIMITED (JP) 2009-07-09 US disclosed