Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.64 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15586041 | 0.91 | CYP4A11 (0.75) | CYP4A11CYP4F2ALDH1A1GFERGAA | |
| SCHEMBL1161121 | 0.91 | CYP4F2 (0.63) | CYP4A11CYP4F2ALDH1A1GFERGAA | |
| Hydrochloric Acid SCHEMBL6801556 | 0.89 | CYP4F2 (0.61) | CYP4A11CYP4F2ALDH1A1GFERGAA | |
| SCHEMBL11493064 | 0.87 | CYP4A11 (0.75) | CYP4A11CYP4F2ALDH1A1GFERGAA | |
| SCHEMBL9689657 | 0.86 | MAOB (0.48) | CYP4A11CYP4F2MAOBHPGD | |
| SCHEMBL23200335 | 0.85 | HPGD (0.49) | CYP4A11CYP4F2ALDH1A1GAAMAOB | |
| SCHEMBL17262795 | 0.85 | HPGD (0.49) | CYP4A11CYP4F2ALDH1A1GAAMAOB | |
| SCHEMBL11131179 | 0.85 | CYP4A11 (0.62) | CYP4A11CYP4F2ALDH1A1GFERGAA | |
| SCHEMBL7996038 | 0.84 | CYP4F2 (0.56) | CYP4A11CYP4F2ALDH1A1GFERGAA | |
| SCHEMBL1351101 | 0.84 | TSHR (0.48) | CYP4A11CYP4F2GFERMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140081017-A1 | Histone Deacetylase Inhibitors for Enhancing Activity of Antifungal Agents | METHYLGENE INC. (CA) | 2014-03-20 | — | — | US | disclosed |
| US-20140081017-A1 | Histone Deacetylase Inhibitors for Enhancing Activity of Antifungal Agents | METHYLGENE INC. (CA) | 2014-03-20 | — | — | US | disclosed |
| US-20140081017-A1 | Histone Deacetylase Inhibitors for Enhancing Activity of Antifungal Agents | METHYLGENE INC. (CA) | 2014-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140081017-A1 | Histone Deacetylase Inhibitors for Enhancing Activity of Antifungal Agents | HDAC1, HDAC5, HDAC7 | CYP4A11 840/4885CYP4F2 2410/4885ALDH1A1 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.