Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17262795 | 0.98 | HPGD (0.49) | MAOBEPHX2TSHRHPGDCYP4A11 | |
| SCHEMBL23200335 | 0.98 | HPGD (0.49) | MAOBEPHX2TSHRHPGDCYP4A11 | |
| SCHEMBL1351101 | 0.95 | TSHR (0.48) | MAOBEPHX2TSHRCYP4A11CYP4F2 | |
| Hydrochloric Acid SCHEMBL1789073 | 0.93 | MAOB (0.47) | MAOBEPHX2TSHRCYP4A11CYP4F2 | |
| SCHEMBL1310411 | 0.90 | EPHX2 (0.45) | MAOBEPHX2TSHRCYP4A11CYP4F2 | |
| SCHEMBL223653 | 0.87 | CYP4F2 (0.50) | EPHX2TSHRCYP4A11CYP4F2 | |
| SCHEMBL15522658 | 0.86 | CYP4A11 (0.64) | MAOBHPGDCYP4A11CYP4F2 | |
| Hydrochloric Acid SCHEMBL7282073 | 0.86 | CYP4F2 (0.49) | MAOBEPHX2CYP4A11CYP4F2 | |
| SCHEMBL22921868 | 0.85 | TSHR (0.58) | EPHX2TSHRCYP4A11CYP4F2CYP4Z1 | |
| SCHEMBL2158877 | 0.84 | CALM1 (0.53) | EPHX2TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104130247-A | Human T2R bitter taste receptors and the use thereof | SENOMYX INC | 2014-11-05 | — | — | CN | disclosed |
| CN-101828111-B | Human T2R bitter taste receptor and uses thereof | SENOMYX INC | 2014-07-23 | — | — | CN | disclosed |
| CN-101828111-A | Human T2R bitter taste receptor and uses thereof | SENOMYX INC | 2010-09-08 | — | — | CN | disclosed |
| CN-1366524-A | Sulfonamide Derivatives as Matrix Metalloproteinase Inhibitors | SAMSUNG ELECTRONICS CO LTD (KR) | 2002-08-28 | — | — | CN | disclosed |
| EP-0181592-B1 | USE OF SPERGUALIN DERIVATIVES FOR THE PREPARATION OF MEDICAMENTS HAVING IMMUNOSUPPRESSIVE ACTIVITY | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-4851446-A | SPERGUALIN-LIKE GUANIDINES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0153720-B1 | SPERGUALIN-RELATED COMPOUNDS HAVING A PHENYLENE GROUP, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1988-11-09 | — | — | EP | disclosed |
| CN-85101425-A | Have Si Baige Eyring allied compound of phenylene and preparation method thereof | — | 1987-01-17 | — | — | CN | disclosed |
| EP-0181592-A2 | Use of spergualin derivatives for the preparation of medicaments having immunosuppressive activity | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1986-05-21 | — | — | EP | disclosed |
| US-4556735-A | BACTERICIDE, ANTITUMOR AGENT | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYUKAI (JP) | 1985-12-03 | — | — | US | disclosed |
| EP-0153720-A2 | Spergualin-related compounds having a phenylene group, a process for their preparation and their use as medicaments | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1985-09-04 | — | — | EP | disclosed |