SCHEMBL7996038

SCHEMBL7996038

COC(=O)Cc1ccc(N)cc1.Nc1ccc(CC(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.56
CYP4A11 Q02928 1/20 0.56
ALDH1A1 P00352 6/20 0.54
GAA P10253 4/20 0.54
GFER P55789 1/20 0.54
KDM4E B2RXH2 2/20 0.47
POLB P06746 1/20 0.47
TSHR P16473 2/20 0.47
NFKB1 P19838 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CA2 P00918 1/20 0.47
CAMK2A Q9UQM7 1/20 0.47
HSP90AB1 P08238 1/20 0.46
AKR1B1 P15121 1/20 0.45
LMNA P02545 2/20 0.45
HPGD P15428 2/20 0.44
HSD17B10 Q99714 1/20 0.44
SLC7A5 Q01650 1/20 0.44
PTGS1 P23219 2/20 0.44
ABCC4 O15439 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1161121 0.93 CYP4F2 (0.63) CYP4F2CYP4A11ALDH1A1GAAGFER
Hydrochloric Acid SCHEMBL6801556 0.91 CYP4F2 (0.61) CYP4F2CYP4A11ALDH1A1GAAGFER
SCHEMBL4104271 0.91 CYP4F2 (0.66) CYP4F2CYP4A11ALDH1A1GAAGFER
SCHEMBL1331730 0.84 CA2 (0.62) ALDH1A1GAAGFERKDM4EPOLB
SCHEMBL39103 0.84 CA2 (0.62) ALDH1A1GAAGFERKDM4EPOLB
SCHEMBL15522658 0.84 CYP4A11 (0.64) CYP4F2CYP4A11ALDH1A1GAAGFER
SCHEMBL7071058 0.83 CYP4F2 (0.53) CYP4F2CYP4A11ALDH1A1GAAGFER
Bromide SCHEMBL25328791 0.82 CA2 (0.60) ALDH1A1GAAGFERKDM4EPOLB
SCHEMBL9644299 0.82 CA2 (0.60) ALDH1A1GAAGFERKDM4EPOLB
Hydrochloric Acid SCHEMBL5002464 0.82 CA2 (0.60) ALDH1A1GAAGFERKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001055140-A1 ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES SYNGENTA LIMITED (GB) 2001-08-02 WO disclosed