Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 15/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15522985 | 1.00 | GPR52 (0.47) | GPR52HDAC4HDAC1NPC1RAB9A | |
| SCHEMBL11332451 | 0.78 | TDP1 (0.47) | HDAC4HDAC1 | |
| SCHEMBL21654213 | 0.74 | MEN1 (0.46) | HDAC4HDAC1 | |
| SCHEMBL15366286 | 0.74 | MEN1 (0.46) | HDAC4HDAC1 | |
| SCHEMBL24401235 | 0.73 | TDP1 (0.60) | NPC1RAB9A | |
| SCHEMBL9268265 | 0.71 | GPR52 (0.54) | GPR52HDAC1 | |
| SCHEMBL5020594 | 0.71 | GPR52 (0.54) | GPR52HDAC1 | |
| SCHEMBL17491863 | 0.71 | KMT2A (0.54) | HDAC4HDAC1NPC1RAB9AHCAR2 | |
| SCHEMBL17491864 | 0.71 | KMT2A (0.54) | HDAC4HDAC1NPC1RAB9AHCAR2 | |
| SCHEMBL15522925 | 0.70 | TDP1 (0.56) | HDAC4HDAC1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140081017-A1 | Histone Deacetylase Inhibitors for Enhancing Activity of Antifungal Agents | METHYLGENE INC. (CA) | 2014-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140081017-A1 | Histone Deacetylase Inhibitors for Enhancing Activity of Antifungal Agents | HDAC1, HDAC5, HDAC7 | GPR52 3920/4885HDAC4 9/4885HDAC1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.