Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 13/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | EBP | Q15125 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020594 | 1.00 | GPR52 (0.54) | GPR52LMNAHTTEBPSIGMAR1 | |
| SCHEMBL27690340 | 0.90 | NAMPT (0.56) | GPR52LMNAHTTEBPSIGMAR1 | |
| SCHEMBL10636333 | 0.87 | KMT2A (0.54) | GPR52LMNA | |
| SCHEMBL10636324 | 0.87 | KMT2A (0.54) | GPR52LMNA | |
| SCHEMBL1981146 | 0.83 | RARA (0.58) | LMNAHTTRARARARBRARG | |
| SCHEMBL1981144 | 0.83 | RARA (0.58) | LMNAHTTRARARARBRARG | |
| SCHEMBL9504867 | 0.82 | GPR52 (0.48) | GPR52 | |
| SCHEMBL9504873 | 0.82 | GPR52 (0.48) | GPR52 | |
| SCHEMBL16050170 | 0.82 | AKR1B1 (0.55) | GPR52LMNAHTTNAMPT | |
| SCHEMBL16050173 | 0.82 | AKR1B1 (0.55) | GPR52LMNAHTTNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464865-A | Enzyme inhibitors as antiinflammatory agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| US-4757078-A | Antiinflammatory agents, psoriasis | E. R. SQUIBB & SONS, INC. (US) | 1988-07-12 | — | — | US | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |