Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840905 | 0.83 | P2RX4 (0.36) | P2RX4P2RX1P2RX3P2RX7LMNA | |
| SCHEMBL4730217 | 0.82 | P2RX4 (0.35) | P2RX4P2RX1P2RX3P2RX7LMNA | |
| SCHEMBL28711618 | 0.78 | GSK3B (0.40) | GSK3BP2RX4KCNH2P2RX1P2RX3 | |
| SCHEMBL7757567 | 0.75 | — | — | |
| SCHEMBL10841349 | 0.73 | GLA (0.35) | — | |
| SCHEMBL3730203 | 0.73 | GPR84 (0.35) | — | |
| SCHEMBL20291578 | 0.73 | CA12 (0.39) | — | |
| SCHEMBL7035805 | 0.70 | — | — | |
| SCHEMBL5401292 | 0.70 | — | — | |
| SCHEMBL5231214 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313183-A1 | LIGAND FUNCTIONALIZED SUBSTRATES | 3M Innovative Properties Company (US) | 2011-04-27 | — | — | EP | disclosed |
| WO-2009146321-A1 | LIGAND FUNCTIONALIZED SUBSTRATES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-12-03 | — | — | WO | disclosed |