Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 13/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840905 | 0.85 | P2RX4 (0.36) | P2RX4P2RX1P2RX3P2RX7LMNA | |
| SCHEMBL1552327 | 0.82 | GSK3B (0.38) | P2RX4P2RX1P2RX3P2RX7LMNA | |
| SCHEMBL20291578 | 0.77 | CA12 (0.39) | SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL284852 | 0.77 | SMN1; SMN2 (0.39) | TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL7757567 | 0.77 | — | — | |
| SCHEMBL10841349 | 0.75 | GLA (0.35) | SMN1; SMN2 | |
| SCHEMBL3730203 | 0.75 | GPR84 (0.35) | — | |
| SCHEMBL5401292 | 0.71 | — | — | |
| SCHEMBL7035805 | 0.71 | — | — | |
| SCHEMBL8060205 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121029-A2 | USE OF 9-OXOACRIDINE-10-ACETIC ACID AND/OR SALTS AND/OR ITS ESTERS THEREOF FOR THE TREATMENT AND PROPHYLAXIS OF MALIGNANT TUMORS OF FEMALE REPRODUCTIVE SYSTEM | SURKOV KIRILL GENNEDIEVICH (RU) | 2008-10-09 | — | — | WO | claimed |
| WO-2008121028-A2 | USE OF 9-OXOACRIDINE-10-ACETIC ACID, SALTS AND ESTERS THEREOF IN COMBINATION THERAPY OF OVARIAN CANCER | SURKOV KIRILL GENNEDIEVICH (RU) | 2008-10-09 | — | — | WO | claimed |
| WO-2008024027-A2 | USE OF 9-OXOACRIDINE-10-ACETIC ACID, ITS SALTS AND ESTERS FOR ENHANCING THE EFFICACY OF ANTIANDROGENIC TREATMENT | SURKOV KIRILL GENNADIEVICH (RU) | 2008-02-28 | — | — | WO | claimed |