SCHEMBL15524151

SCHEMBL15524151

C=Cc1ccc(CBr)c(OCC)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
TRPA1 O75762 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.39
TOP2A P11388 1/20 0.37
ABL1 P00519 1/20 0.36
ABCB1 P08183 1/20 0.36
BCR P11274 1/20 0.36
LMNA P02545 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
TUBB1 Q9H4B7 3/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15524876 0.87 KDM4E (0.40) ALDH1A1TRPA1MEN1KMT2AKDM4E
SCHEMBL15524385 0.87 ALDH1A1 (0.41) ALDH1A1TRPA1MEN1KMT2AKDM4E
SCHEMBL16955987 0.86 ALDH1A1 (0.47) ALDH1A1TRPA1MEN1KMT2AKDM4E
SCHEMBL16959275 0.83 ALDH1A1 (0.41) ALDH1A1TRPA1MEN1KMT2AKDM4E
SCHEMBL14760792 0.83 ALDH1A1 (0.41) ALDH1A1TRPA1MEN1KMT2AKDM4E
SCHEMBL14761112 0.83 TRPA1 (0.56) ALDH1A1TRPA1TUBB1TUBB4ATUBB
SCHEMBL14761015 0.81 ALDH1A1 (0.40) ALDH1A1TRPA1MEN1KMT2AKDM4E
SCHEMBL31619156 0.80 ALDH1A1 (0.51) ALDH1A1TRPA1MEN1KMT2AKDM4E
SCHEMBL6198028 0.80 ALDH1A1 (0.51) ALDH1A1TRPA1MEN1KMT2AKDM4E
SCHEMBL16957857 0.79 ALDH1A1 (0.44) ALDH1A1TRPA1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9079989-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-07-14 US disclosed
US-20150025213-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-01-22 US disclosed
US-8883946-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-11-11 US disclosed
US-20140080989-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-03-20 US disclosed