SCHEMBL1552464

SCHEMBL1552464

CCS(=O)(=O)[O-].CCS(=O)(=O)[O-].[Mg+2]

nearest known ligand 0.38

Known targets — ChEMBL curated mechanism

FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BBOX1 O75936 3/20 0.38
KDM4E B2RXH2 2/20 0.37
MAPT P10636 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 3/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPK1 P28482 2/20 0.33
TP53 P04637 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GMNN O75496 1/20 0.33
LMNA P02545 1/20 0.33
THPO P40225 1/20 0.33
HBB P68871 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RECQL P46063 2/20 0.32
GLA P06280 1/20 0.32
HPGD P15428 1/20 0.32
EPHX2 P34913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28608963 0.96
SCHEMBL19809549 0.91 BBOX1 (0.38) BBOX1KDM4EMAPTALOX15TSHR
SCHEMBL2367141 0.91 BBOX1 (0.38) BBOX1KDM4EMAPTALOX15TSHR
Zinc Ion SCHEMBL428649 0.91 BBOX1 (0.38) BBOX1KDM4EMAPTALOX15TSHR
SCHEMBL20533647 0.91 BBOX1 (0.38) BBOX1KDM4EMAPTALOX15TSHR
SCHEMBL20583852 0.91 BBOX1 (0.38) BBOX1KDM4EMAPTALOX15TSHR
SCHEMBL20533678 0.91
SCHEMBL22581623 0.91 BBOX1 (0.38) BBOX1KDM4EMAPTALOX15TSHR
SCHEMBL20533681 0.91 BBOX1 (0.38) BBOX1KDM4EMAPTALOX15TSHR
SCHEMBL9001604 0.91 BBOX1 (0.38) BBOX1KDM4EMAPTALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952059-B2 Acetyl L-carnitine for the preparation of a medicament for the prevention of painful peripheral neuropathy in patients with type 2 diabetes Sigma-Tau Industrie Faramceutiche Riunite S.p.A. (IT) 2015-02-10 US claimed
US-20140024712-A1 ACETYL L-CARNITINE FOR THE PREPARATION OF A MEDICAMENT FOR THE PREVENTION OF PAINFUL PERIPHERAL NEUROPATHY IN PATIENTS WITH TYPE 2 DIABETES SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2014-01-23 US claimed
US-8569366-B2 Acetyl L-carnitine for prevention of painful peripheral neuropathy in patients with type 2 diabetes SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2013-10-29 US claimed
EP-0974582-B1 Process for the preparation of 4-substituted azetidinone derivatives TAKASAGO PERFUMERY CO LTD (JP) 2003-02-12 EP claimed
EP-3601471-A1 ANTI-FREEZE ANTI-CORROSION CONCENTRATES BASF SE (DE) 2020-02-05 EP disclosed
WO-2018172064-A1 ANTI-FREEZE ANTI-CORROSION CONCENTRATES BASF SE (DE) 2018-09-27 WO disclosed
US-8454854-B2 Glycerin-containing antifreezing agent concentrates with corrosion protection BASF SE (DE) 2013-06-04 US disclosed
US-20130105407-A1 GLYCERIN-CONTAINING ANTIFREEZING AGENT CONCENTRATES WITH CORROSION PROTECTION KORMANN CLAUDIUS (DE) 2013-05-02 US disclosed
US-20110163260-A1 GLYCERIN-CONTAINING ANTIFREEZING AGENT CONCENTRATES WITH CORROSION PROTECTION BASF AG (DE) 2011-07-07 US disclosed
EP-1859002-B1 ANTIFREEZE CONCENTRATES COMPRISING GLYCERINE WITH CORROSION PROTECTION BASF SE (DE) 2011-04-27 EP disclosed
US-7927505-B2 preparing from superconcentrates; also monohydric, dihydric, trihydric and poly alcohols other than glycerol, BASF AKTIENGESELLSCHAFT (DE) 2011-04-19 US disclosed
US-20080149883-A1 Glycerin-Containing Antifreezing Agent Concentrates With Corrosion Protection BASF AKIENGESELLSCHAFT (DE) 2008-06-26 US disclosed
EP-1859002-A1 ANTIFREEZE CONCENTRATES COMPRISING GLYCERINE WITH CORROSION PROTECTION BASF AKTIENGESELLSCHAFT (DE) 2007-11-28 EP disclosed
WO-2006092376-A1 GLYCERIN-CONTAINING ANTIFREEZING AGENT CONCENTRATES WITH CORROSION PROTECTION BASF AKTIENGESELLSCHAFT (DE) 2006-09-08 WO disclosed
US-5744678-A NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed