SCHEMBL15525192

SCHEMBL15525192

C=C(C)C(=O)NC(CC)[Si]1(O)CCCCO1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21372373 0.66
SCHEMBL5024533 0.65
SCHEMBL15525009 0.62 TGFBR1 (0.34) TGFBR1
SCHEMBL11674951 0.62 TGFBR1 (0.50) TGFBR1
SCHEMBL154480 0.62 TGFBR1 (0.50) TGFBR1
SCHEMBL15322737 0.62 TGFBR1 (0.50) TGFBR1
SCHEMBL388659 0.62
SCHEMBL6036462 0.61 TSHR (0.30)
SCHEMBL28103168 0.60 TGFBR1 (0.48) TGFBR1
SCHEMBL554944 0.60 TGFBR1 (0.48) TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2838905-B1 NOVEL, MONO-SYNTHESIZABLE, SPONTANEOUSLY WATER-SOLUBLE, SUBSTANTIALLY VOC-FREE, ENVIRONMENTALLY FRIENDLY (METH)ACRYLAMIDO-FUNCTIONAL SILOXANOL SYSTEMS, PROCESS FOR THEIR PREPARATION AND USE EVONIK DEGUSSA GMBH (DE) 2019-09-25 EP disclosed
US-9765095-B2 Easily synthesizable, spontaneously water-soluble, essentially voc-free, environmentally friendly (meth)acrylamido-functional siloxanol systems, process for preparation thereof and use EVONIK DEGUSSA GMBH (DE) 2017-09-19 US disclosed
US-9409930-B2 Easily synthesizable, spontaneously water-soluble, essentially VOC-free, environmentally friendly (meth)acrylamido-functional siloxanol systems, process for preparation thereof and use EVONIK DEGUSSA GMBH (DE) 2016-08-09 US disclosed
US-20160222038-A1 NOVEL, EASILY SYNTHESIZABLE, SPONTANEOUSLY WATER-SOLUBLE, ESSENTIALLY VOC-FREE, ENVIRONMENTALLY FRIENDLY (METH)ACRYLAMIDO-FUNCTIONAL SILOXANOL SYSTEMS, PROCESS FOR PREPARATION THEREOF AND USE EVONIK INDUSTRIES AG (DE) 2016-08-04 US disclosed
US-20150080594-A1 NOVEL, EASILY SYNTHESIZABLE, SPONTANEOUSLY WATER-SOLUBLE, ESSENTIALLY VOC-FREE, ENVIRONMENTALLY FRIENDLY (METH)ACRYLAMIDO-FUNCTIONAL SILOXANOL SYSTEMS, PROCESS FOR PREPARATION THEREOF AND USE EVONIK INDUSTRIES AG (DE) 2015-03-19 US disclosed
EP-2838905-A1 NOVEL, MONO-SYNTHESIZABLE, SPONTANEOUSLY WATER-SOLUBLE, SUBSTANTIALLY VOC-FREE, ENVIRONMENTALLY FRIENDLY (METH)ACRYLAMIDO-FUNCTIONAL SILOXANOL SYSTEMS, PROCESS FOR THEIR PREPARATION AND USE Evonik Industries AG (DE) 2015-02-25 EP disclosed
WO-2013156185-A1 NOVEL, MONO-SYNTHESIZABLE, SPONTANEOUSLY WATER-SOLUBLE, SUBSTANTIALLY VOC-FREE, ENVIRONMENTALLY FRIENDLY (METH)ACRYLAMIDO-FUNCTIONAL SILOXANOL SYSTEMS, PROCESS FOR THEIR PREPARATION AND USE EVONIK INDUSTRIES AG (DE) 2013-10-24 WO disclosed