⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27667519 | 0.71 | — | — | |
| SCHEMBL10344543 | 0.69 | TSHR (0.36) | — | |
| SCHEMBL322752 | 0.66 | — | — | |
| SCHEMBL15525192 | 0.66 | TGFBR1 (0.33) | — | |
| SCHEMBL27389968 | 0.62 | TSHR (0.49) | — | |
| Methacrylic Acid SCHEMBL3360717 | 0.62 | — | — | |
| Methacrylic Acid SCHEMBL440899 | 0.62 | — | — | |
| SCHEMBL15161888 | 0.61 | — | — | |
| SCHEMBL27550344 | 0.60 | ALDH1A1 (0.52) | — | |
| SCHEMBL5024468 | 0.60 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838905-B1 | NOVEL, MONO-SYNTHESIZABLE, SPONTANEOUSLY WATER-SOLUBLE, SUBSTANTIALLY VOC-FREE, ENVIRONMENTALLY FRIENDLY (METH)ACRYLAMIDO-FUNCTIONAL SILOXANOL SYSTEMS, PROCESS FOR THEIR PREPARATION AND USE | EVONIK DEGUSSA GMBH (DE) | 2019-09-25 | — | — | EP | disclosed |
| CN-104220489-B | Easy preparation, the siloxane systems, preparation method and use of low VOC environmental protection (methyl) acrylamido function | 赢创德固赛有限公司 | 2017-09-05 | — | — | CN | disclosed |
| CN-104220489-A | Novel, easily producible, voc-reduced, environmentally friendly (meth)acrylamido-functional siloxane systems, processes for the preparation and uses thereof | EVONIK INDUSTRIES AG | 2014-12-17 | — | — | CN | disclosed |