SCHEMBL15525263

SCHEMBL15525263

O=Cc1cc(CS)ncc1Cl

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.34
ERN1 O75460 2/20 0.32
ALDH1A1 P00352 1/20 0.32
ORAI1 Q96D31 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1533918 0.74 TDP1 (0.40) TDP1ERN1ALDH1A1ORAI1
SCHEMBL30589401 0.74 TDP1 (0.40) TDP1ERN1ALDH1A1ORAI1
SCHEMBL662543 0.73 ALDH1A1 (0.35) TDP1ALDH1A1ORAI1
SCHEMBL29951024 0.71 ERN1 (0.44) TDP1ERN1ALDH1A1
SCHEMBL29953875 0.71 CYP1A2 (0.38) TDP1ERN1ALDH1A1
SCHEMBL29951690 0.71 TDP1 (0.38) TDP1ERN1ALDH1A1ORAI1
SCHEMBL660973 0.71 TDP1 (0.38) TDP1ERN1ALDH1A1ORAI1
SCHEMBL15012943 0.71 TDP1 (0.38) TDP1ERN1ALDH1A1
SCHEMBL31723867 0.71 TDP1 (0.38) TDP1ERN1ALDH1A1ORAI1
SCHEMBL15525262 0.68 TDP1 (0.35) TDP1ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013158422-A1 HETEROCYCLIC COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-10-24 WO disclosed