Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 6/20 | 0.36 |
| ▸ | NOS1 | P29475 | 6/20 | 0.36 |
| ▸ | NOS2 | P35228 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | INMT | O95050 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957 | 1.00 | NISCH (0.39) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL14993023 | 1.00 | NISCH (0.39) | NISCHNOS3NOS1NOS2MEN1 | |
| Hydrochloric Acid SCHEMBL4047505 | 0.98 | NOS3 (0.38) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL4613968 | 0.98 | NISCH (0.35) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL14993410 | 0.95 | NOS3 (0.41) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL5011983 | 0.95 | NOS3 (0.41) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL15743712 | 0.95 | NOS3 (0.41) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL4649152 | 0.95 | NOS3 (0.41) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL22477358 | 0.95 | NOS3 (0.41) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL4611302 | 0.95 | NOS3 (0.41) | NISCHNOS3NOS1NOS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838934-A2 | MOSITURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | Momentive Performance Materials Inc. (US) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013158236-A2 | MOSITURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-10-24 | — | — | WO | disclosed |