Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 7/20 | 0.41 |
| ▸ | NOS1 | P29475 | 7/20 | 0.41 |
| ▸ | NOS2 | P35228 | 7/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | INMT | O95050 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14993410 | 1.00 | NOS3 (0.41) | NOS3NOS1NOS2NISCHMEN1 | |
| SCHEMBL15743712 | 1.00 | NOS3 (0.41) | NOS3NOS1NOS2NISCHMEN1 | |
| SCHEMBL4649152 | 1.00 | NOS3 (0.41) | NOS3NOS1NOS2NISCHMEN1 | |
| SCHEMBL4611302 | 1.00 | NOS3 (0.41) | NOS3NOS1NOS2NISCHMEN1 | |
| SCHEMBL22477358 | 1.00 | NOS3 (0.41) | NOS3NOS1NOS2NISCHMEN1 | |
| SCHEMBL6498120 | 0.98 | NOS1 (0.39) | NOS3NOS1NOS2NISCHMEN1 | |
| SCHEMBL29957 | 0.95 | NISCH (0.39) | NOS3NOS1NOS2NISCHMEN1 | |
| SCHEMBL15526124 | 0.95 | NISCH (0.39) | NOS3NOS1NOS2NISCHMEN1 | |
| SCHEMBL14993023 | 0.95 | NISCH (0.39) | NOS3NOS1NOS2NISCHMEN1 | |
| SCHEMBL4649825 | 0.95 | NISCH (0.39) | NOS3NOS1NOS2NISCHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785726-A2 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF; AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | Dow Corning Corporation (US) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013081820-A2 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF;AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | DOW CORNING CORPORATION (US) | 2013-06-06 | — | — | WO | disclosed |
| EP-1965902-A1 | CONTINIUOUS FLOW REACTOR | Fluens Synthesis AS (NO) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007058544-A1 | CONTINIUOUS FLOW REACTOR | FLUENS SYNTHESIS AS (NO) | 2007-05-24 | — | — | WO | disclosed |
| EP-1051425-A2 | 2-(PURIN-9-yl)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999038877-A2 | 2-(PURIN-9-yl)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-08-05 | — | — | WO | disclosed |