Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | FPR1 | P21462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15526304 | 0.84 | KDM4E (0.32) | KDM4ETDP1L3MBTL1MAPTRXFP1 | |
| SCHEMBL15526307 | 0.84 | MAPT (0.35) | KDM4ETDP1L3MBTL1MAPTRXFP1 | |
| SCHEMBL15526287 | 0.82 | MAPT (0.33) | KDM4EMAPTRXFP1ALDH1A1MEN1 | |
| SCHEMBL15526212 | 0.81 | KDM4E (0.35) | KDM4ETDP1L3MBTL1MAPTRXFP1 | |
| SCHEMBL15526313 | 0.81 | CDK2 (0.35) | L3MBTL1MAPTRXFP1MEN1KMT2A | |
| SCHEMBL15526228 | 0.80 | MAPT (0.35) | KDM4ETDP1L3MBTL1MAPTRXFP1 | |
| SCHEMBL15526184 | 0.79 | NMT1 (0.39) | MCHR1 | |
| SCHEMBL15526295 | 0.77 | MAP4K1 (0.32) | MAPTRXFP1 | |
| SCHEMBL15526316 | 0.77 | NAMPT (0.33) | KDM4ETDP1MAPTHPGDALDH1A1 | |
| SCHEMBL20030995 | 0.76 | KDM4E (0.43) | KDM4ETDP1L3MBTL1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788336-A1 | BENZOTHIAZOL- 6 -YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | Gilead Sciences, Inc. (US) | 2014-10-15 | — | — | EP | disclosed |
| WO-2013159064-A1 | BENZOTHIAZOL- 6 -YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES, INC. (US) | 2013-10-24 | — | — | WO | disclosed |