Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19905916 | 0.87 | KDM4E (0.40) | NAMPTTBXAS1KDM4EALDH1A1HPGD | |
| SCHEMBL15526315 | 0.84 | KDM4E (0.34) | NAMPTTBXAS1KDM4EALDH1A1HPGD | |
| SCHEMBL15526212 | 0.83 | KDM4E (0.35) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL15526307 | 0.79 | MAPT (0.35) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL15342392 | 0.78 | CDC7 (0.35) | NAMPTKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL15342020 | 0.77 | CYP3A4 (0.33) | NAMPTTBXAS1KDM4EALDH1A1HPGD | |
| SCHEMBL15333463 | 0.77 | CYP3A4 (0.39) | NAMPTTBXAS1KDM4EALDH1A1HPGD | |
| SCHEMBL15334233 | 0.77 | CYP3A4 (0.39) | NAMPTTBXAS1KDM4EALDH1A1HPGD | |
| SCHEMBL15526288 | 0.77 | KDM4E (0.33) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL15526228 | 0.77 | MAPT (0.35) | KDM4EALDH1A1HPGDMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788336-A1 | BENZOTHIAZOL- 6 -YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | Gilead Sciences, Inc. (US) | 2014-10-15 | — | — | EP | disclosed |
| WO-2013159064-A1 | BENZOTHIAZOL- 6 -YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES, INC. (US) | 2013-10-24 | — | — | WO | disclosed |