SCHEMBL1552675

SCHEMBL1552675

c1ccc2oc(Cn3ccnc3)cc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 10/20 1.00
▸ CYP11B1 P15538 7/20 0.67
▸ CYP11B2 P19099 6/20 0.67
▸ TBXAS1 P24557 2/20 0.62
▸ CYP17A1 P05093 1/20 0.53
▸ POLB P06746 2/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ CYP2D6 P10635 1/20 0.50
▸ MAPT P10636 1/20 0.50
▸ QPCT Q16769 1/20 0.50
▸ CYP4Z1 Q86W10 1/20 0.50
▸ QPCTL Q9NXS2 1/20 0.50
▸ NAMPT P43490 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8909610 0.80 CYP19A1 (0.67) CYP19A1
SCHEMBL7297515 0.80 CYP11B1 (1.00) CYP19A1CYP11B1CYP11B2CYP17A1
SCHEMBL27581650 0.80 CYP19A1 (0.66) CYP19A1CYP11B1CYP11B2TBXAS1NAMPT
Hydrochloric Acid SCHEMBL10537421 0.77 CYP19A1 (0.62) CYP19A1CYP11B1CYP11B2CYP17A1POLB
SCHEMBL15754429 0.74 CYP11B1 (1.00) CYP19A1CYP11B1CYP11B2
SCHEMBL1171161 0.74 CYP19A1 (0.58) CYP19A1CYP11B1CYP11B2TBXAS1CYP17A1
SCHEMBL11006233 0.71 CYP19A1 (0.54) CYP19A1CYP11B1CYP11B2NAMPT
SCHEMBL8865557 0.70 CYP19A1 (1.00) CYP19A1CYP11B1CYP11B2TBXAS1CYP17A1
SCHEMBL563349 0.70 CYP19A1 (0.54) CYP19A1CYP11B1CYP11B2CYP1A2CYP3A4
SCHEMBL27705085 0.70 POLB (0.62) CYP19A1CYP11B1CYP11B2TBXAS1CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11974977-B2 Composition and uses for influencing hair growth LUCOLAS—M.D. LTD (GB) 2024-05-07 — — US disclosed
US-11324711-B2 Composition and uses for influencing hair growth S.W. PATENTVERWERTUNGS LIMITED (GB) 2022-05-10 — — US disclosed
US-20210290579-A1 COMPOSITION AND USES FOR INFLUENCING HAIR GROWTH LUCOLAS M D LTD (GB) 2021-09-23 — — US disclosed
US-11052059-B2 Composition and uses for influencing hair growth LUCOLAS - M.D. LTD (GB) 2021-07-06 — — US disclosed
EP-2262471-B1 COMPOSITION AND USES FOR INFLUENCING HAIR GROWTH LUCOLAS M D LTD (GB) 2015-10-28 — — EP disclosed
US-20130142890-A1 COMPOSITION AND USES FOR INFLUENCING HAIR GROWTH S.W. PATENTVERWERTUNGS LIMITED (GB) 2013-06-06 — — US disclosed
US-8278291-B1 Treatment of wrinkles and strias with 4-hydroxyandrostenedione or a derivative thereof CURADIS GMBH (DE) 2012-10-02 — — US disclosed
US-20110117218-A1 composition and uses for influencing hair growth S.W. Patenverwertwertungs Limited (GB) 2011-05-19 — — US disclosed
EP-1253966-B1 SUBSTANCES AND AGENTS FOR POSITIVELY INFLUENCING COLLAGEN CURADIS GMBH (DE) 2011-04-27 — — EP disclosed
EP-2262471-A2 COMPOSITION AND USES FOR INFLUENCING HAIR GROWTH S.w. Patentverwertungs Limited (GB) 2010-12-22 — — EP disclosed
WO-2009109402-A2 COMPOSITION AND USES FOR INFLUENCING HAIR GROWTH S.W. PATENTVERWERTUNGS LIMITED (GB) 2009-09-11 — — WO disclosed
US-20070148123-A1 Substances and agents for positively influencing collagen WIELAND HEINRICH 2007-06-28 — — US disclosed
EP-1414467-A2 TOPICAL TREATMENT FOR MASTALGIA Schmidt, Alfred (DE) 2004-05-06 — — EP disclosed
US-20040018991-A1 Topical treatment for mastalgia MDI ONCOLOGY, INC. 2004-01-29 — — US disclosed
EP-1253966-A2 SUBSTANCES AND AGENTS FOR POSITIVELY INFLUENCING COLLAGEN Wieland, Heinrich (DE) 2002-11-06 — — EP disclosed
WO-2002036129-A2 TOPICAL TREATMENT OF MASTALGIA WITH AROMETESE INHIBITORS SUCH AS ANDROSTENDIONE SCHMIDT ALFRED (DE) 2002-05-10 — — WO disclosed
WO-2001012206-A2 SOY-GLYCINE EXTRACTS AND AROMATASE INHIBITORS FOR POSITIVELY INFLUENCING COLLAGEN WIELAND HEINRICH (DE) 2001-02-22 — — WO disclosed
EP-0514198-B1 1H-Imidazol-1-yl-methyl benzofuran derivatives with the imidazolyl moiety being substituted by a cycloalkyl group GLAXO GROUP LTD (GB) 1998-08-05 — — EP disclosed
EP-0514198-A1 1H-Imidazol-1-yl-methyl benzofuran derivatives with the imidazolyl moiety being substituted by a cycloalkyl group GLAXO GROUP LIMITED (GB) 1992-11-19 — — EP disclosed
EP-0505954-A1 N-Imidazolylmethyl benzofuran derivatives as inhibitors of angiotensin II activity GLAXO GROUP LIMITED (GB) 1992-09-30 — — EP disclosed
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